|
|
| Author |
Message |
Roman Bystrianyk
medicine forum Guru
Joined: 02 May 2005
Posts: 454
|
 Posted: Tue Nov 15, 2005 12:01 am Post subject:
The Nude Mouse Tale: Omega-3 Fats Save The Life Of A Terminal Cancer Patient
|
|
|
"The Nude Mouse Tale: Omega-3 Fats Save The Life Of A Terminal Cancer
Patient", Science Daily, November 14, 2005,
Link: http://www.sciencedaily.com/releases/2005/11/051110083907.htm
Ron Pardini is not a medical doctor. Yet he is seen as a hero by his
cancer-stricken neighbor, "D.H." Pardini helped the 78-year-old
after D.H. was diagnosed with terminal lung cancer.
"In 2000 he was told by his doctor he had only a few months to
live," said Pardini, a professor of biochemistry and associate
director of the Nevada Agricultural Experiment Station at the
University of Nevada, Reno. "But five years later, he is still alive,
and has even gained a little weight."
The cancerous tumors found in D.H.'s lungs have shrunk to 10 percent
of what they were in 2000, according to last year's computed
tomography (CT) scans.
What worked with DH is not a common medical treatment such as
chemotherapy or surgical excision. It was a nutritional intervention,
drastically increasing the patient's intake of omega-3 fatty acids,
which are often found in fish oil or golden algae oil.
Pardini's previous research showed that omega-3 fatty acids
significantly depressed the growth of human mammary, ovarian, colon,
prostate and pancreatic cancer cells that were injected into athymic
mice-also known as nude mice.
His studies also demonstrated that fish oil consumption improves a
mouse's responsiveness to chemotherapy.
Fish oil research was inspired by observations that Inuit Eskimo
populations have less breast and prostate cancer deaths. So far,
though, most studies in this country are limited to animal models, but
a case study about D.H., which was published in the recent issue of the
Nutrition and Cancer journal, could be a major step forward for human
clinical trials.
While beginning to take high dose of fish oil and golden algae oil
capsules daily, D.H. also reduced corn-based foods from his diet. Corn
contains omega-6 fatty acids that Pardini said are found to increase
cancer growth.
Pardini is optimistic of what his findings may contribute to cancer
treatment.
"We have good evidence for employing nutritional interventions to
improve cancer treatment and patient well-being," he said.
Pardini wants to be able to provide viable non-toxic, over-the-counter
solutions for the numerous people with fear of cancer in the back of
their minds. The Nutrition and Cancer article is co-authored by Nevada
nutrition Professor David Wilson and University of Nevada medical
school Professors, Steven Schiff, Stephen Bajo and Randall Pierce. |
|
| Back to top |
|
 |
J
medicine forum Guru
Joined: 29 Apr 2005
Posts: 612
|
| Posted: Tue Nov 15, 2005 1:27 am Post subject:
Re: The Nude Mouse Tale: Omega-3 Fats Save The Life Of A Terminal Cancer Patient
|
|
|
Roman Bystrianyk wrote:
| Quote: | "The Nude Mouse Tale: Omega-3 Fats Save The Life Of A Terminal Cancer
Patient", Science Daily, November 14, 2005,
Link: http://www.sciencedaily.com/releases/2005/11/051110083907.htm
Ron Pardini is not a medical doctor. Yet he is seen as a hero by his
cancer-stricken neighbor, "D.H." Pardini helped the 78-year-old
after D.H. was diagnosed with terminal lung cancer.
"In 2000 he was told by his doctor he had only a few months to
live," said Pardini, a professor of biochemistry and associate
director of the Nevada Agricultural Experiment Station at the
University of Nevada, Reno. "But five years later, he is still alive,
and has even gained a little weight."
The cancerous tumors found in D.H.'s lungs have shrunk to 10 percent
of what they were in 2000, according to last year's computed
tomography (CT) scans.
What worked with DH is not a common medical treatment such as
chemotherapy or surgical excision. It was a nutritional intervention,
drastically increasing the patient's intake of omega-3 fatty acids,
which are often found in fish oil or golden algae oil.
|
They're using it with chemotherapy?
J
http://www.unr.edu/nevadanews/detail.aspx?id=770
Nevada News Image
Ron Pardini’s research shows promise that fish oil, which is high in
omega-3 fatty acids and readily available over-the-counter, can halt cancer
in humans and ease the negative effects of chemotherapy. Photo by Jean
Dixon. (Photo by: Marketing and Communications)
Study focuses on fish oil effect on cancer
Story by: Marketing and Communications
11/20/2003
Your grandmother was right when she told you cod liver oil was good for
you. But she may not have known just how on cue she was.
According to research at the University of Nevada, Reno’s Allie M. Lee
Laboratory for Cancer Research, omega-3 fatty acids, such as those found in
cod liver oil, have an added benefit of combating human cancer -- at least
in laboratory animals injected with human cancer cells.
To test the findings in humans, Ron Pardini, biochemistry professor and
laboratory director, has received a $40,000 grant from Sanford Center for
Aging to study the effects of omega-3 fatty acids in men with prostrate
cancer.
“Preliminary research using mice reveals that fish oil not only depresses
the growth of a variety of cancerous tumors, but it also reduces the spread
of malignant cancer cells,” said Pardini.
These findings support the need for a human clinical trial using omega-3
fatty acids as a nutritional intervention, an area with limited studies
nationwide.
“Who cares if you can treat a mouse?” Pardini said. “We want to treat
people and finally we have that opportunity.”
Pardini will monitor 15 patients with high-risk prostate cancer whose
treatment will be the consumption of large amounts of omega-3 fatty acids.
Pardini’s research has previously found that omega-3 fatty acids
significantly depress the growth of human mammary, ovarian, colon, prostate
and pancreatic cancer cells that were injected into athymic mice -- also
known as nude mice. The studies also show that fish oil consumption
improves the animals’ responsiveness to chemotherapy by several anti-cancer
drugs.
It is Pardini’s hope not only to be able to help the 15 patients in the
clinical trial, but also the more than 200,000 men in the nation who will
be diagnosed this year with prostate cancer and be able to provide viable,
non-toxic, over-the-counter solutions for the numerous people with the fear
of cancer in the back of their minds.
“The critical issue is our diets,” Pardini said. “The U.S. diet is skewed
toward high amounts of omega-6 fatty acids, commonly found in vegetable
oils. We don’t need to exclude omega-6; we need to increase our consumption
of omega-3 fatty acids.”
Omega-3 fat is found in fish and its original source -- algae from lakes
and oceans. Pardini suggests that eating more fish, such as tuna, salmon,
mackerel, lake trout, herring and sardines, or taking fish oil supplements
that are high in DHA and EPA, may be effective ways for increasing dietary
omega-3 fat.
Pardini’s research was spawned by observations that breast and prostate
cancer deaths were lower in Inuit Eskimo populations. The Inuit consume a
high-fat diet, but one that is rich in omega-3 fatty acids.
A team of university nutritionists and medical doctors are assisting
Pardini in the clinical trial. Judith Ashley, a co-principle investigator
and associate professor in the Department of Nutrition, is overseeing the
nutritional aspects of the study.
Roy MacIntosh, professor of internal medicine, is a co-principle
investigator and oncologist who will be recruiting and treating the
patients. Chris Pritsos, an associate professor in the Department of
Nutrition, is responsible for analyzing biochemical effects in the
patients. Gary Cutter, professor of internal medicine, will oversee the
data management for the study and conduct statistical analyses.
By Andrea Paris, (775) 784-4724. |
|
| Back to top |
|
|
Google
|
|
| Back to top |
|
|
|
|
The time now is Thu Jan 08, 2009 1:38 am | All times are GMT
|
|
Car Credit | Secured Loans | Mortgages | Fast Loans | Debt Consolidation
|
|
Copyright © 2004-2005 DeniX Solutions SRL
|
|
Other DeniX Solutions sites:
electronics forum,
Science forum
Unix/Linux blog
Unix/Linux documentation
Unix/Linux forums
|
Powered by phpBB © 2001, 2005 phpBB Group
|
|
FAQ
Search
Memberlist
Usergroups
Register
Profile
Log in to check your private messages
Log in
Forum index
»
diseases
»
cancer
