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new approaches for hepatic cancer?
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Jürgen Schmitz
medicine forum beginner


Joined: 09 Jun 2005
Posts: 3

PostPosted: Thu Jun 09, 2005 7:46 pm    Post subject: new approaches for hepatic cancer? Reply with quote

Hello,

I am doing some research in the internet for a colleague of mine. The person
(female, aged at 70) has fallen ill with hepatic cancer. The diagnosis was
done 2 years ago. The primary tumour proved to be inoperable and metastases
had been found. She suffers from a very inferior quality of life because of
chemotherapy. Some bone preserving medications are given, but as a side
effect of the chemotherapy osteoporosis increasingly causes pain.

The doctor says that therapeutical means have come to an end.

I would like to know in how far there are new approaches available, be it
new medications in testing phase or any other way of alternative therapies.
Any hints? Links?



Thanks, Jürgen
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J
medicine forum addict


Joined: 07 May 2005
Posts: 93

PostPosted: Sat Jun 11, 2005 8:39 pm    Post subject: Re: new approaches for hepatic cancer? Reply with quote

"Jürgen Schmitz" wrote:

Quote:
I am doing some research in the internet for a colleague of mine. The person
(female, aged at 70) has fallen ill with hepatic cancer. The diagnosis was
done 2 years ago. The primary tumour proved to be inoperable and metastases
had been found. She suffers from a very inferior quality of life because of
chemotherapy. Some bone preserving medications are given, but as a side
effect of the chemotherapy osteoporosis increasingly causes pain.

The doctor says that therapeutical means have come to an end.

I would like to know in how far there are new approaches available, be it
new medications in testing phase or any other way of alternative therapies.
Any hints? Links?

Thanks, Jürgen

Hello Jürgen,
I'm sorry to hear about your sister.
You seem to be posting from Europe.
It's my understanding that Europeans get as good cancer care as anywhere else in
the world.
There's lots of experimental drugs being tested in the US and perhaps elsewhere,
but I haven't heard anything earth-shatteringly new and wonderful yet. Clinical
trials take time.

I have heard of arthritic (osteoarthritis) like pain due to chemotherapy.
I'm not sure that I've ever heard of osteoporosis in relation to chemotherapy,
unless the cancer has spread to her bones? If that's the case, radiation
therapy might be helpful for pain, but if she's got osteopososis also, you'd
have to inquire about that. If you want to post more specifics about her bones,
perhaps Steph would reply.

If the doctor's said nothing more can be done, we have to accept it.
Here's a recent Medline Abstract about chemotherapy
http://groups-beta.google.com/group/alt.support.cancer/msg/4befa08191d468b3

Perhaps it's time for you and your sister to discuss quality of life issues.
She may have things she wants to do and places and people she wants to see
if/while she's still well enough.
In Canada and the US, we have hospice (special nursing care which treats to
symptoms and helps the patient have a better qualty of life). I don't know if
you have that in her country or perhaps her family physician can help with that.
The person can stay at home, travel and live the rest of their lives in relative
comfort.

Post anytime or see us on alt.support.cancer for ongoing support.
I'll watch for your updates, on either newsgroup.
You and your sister (and loved ones) will be in my thoughts.
J - not a doctor
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Jürgen Schmitz
medicine forum beginner


Joined: 09 Jun 2005
Posts: 3

PostPosted: Sun Jun 12, 2005 9:18 am    Post subject: Re: new approaches for hepatic cancer? Reply with quote

"J" <Hiss-ss-ss@example.org> wrote...
Quote:
Hello Jürgen,
I'm sorry to hear about your sister.
You seem to be posting from Europe.
Yes, Germany.


Quote:
It's my understanding that Europeans get as good cancer care as anywhere
else in the world.
You are right, they do. I did my posting for two reasons:

- I don´t know the quality of communication in the medicine world. Maybe
there are new approaches which are completely unknown to the doctor.
- My concern is that clinical support is not optimal beacause the doctor has
to take care of many patients at the same time and possibly can give a
standard treatment only for each of them.
So i do some additional research and will ask for his opinion if i will find
news on the subject.

Quote:
There's lots of experimental drugs being tested in the US and perhaps
elsewhere,
but I haven't heard anything earth-shatteringly new and wonderful yet.
Clinical
trials take time.
May be there is a chance not to wait for results but be part of the testing.


Quote:
I have heard of arthritic (osteoarthritis) like pain due to chemotherapy.
I'm not sure that I've ever heard of osteoporosis in relation to
chemotherapy,
unless the cancer has spread to her bones?
Sorry i did the translation by a special dictionary. I am even not sure if i

have chosen the correct german entries in the dictionary. The term
"osteoarthritis" seems to be more appropriate.

Quote:
If the doctor's said nothing more can be done, we have to accept it.
That is true and i will do so if i do not find anything else worth to be

evaluated.

Thank you for yor reply.
Jürgen
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J
medicine forum addict


Joined: 07 May 2005
Posts: 93

PostPosted: Sun Jun 12, 2005 10:05 am    Post subject: Re: new approaches for hepatic cancer? Reply with quote

"Jürgen Schmitz" wrote:

Quote:
"J" <Hiss-ss-ss@example.org> wrote...
[...]
There's lots of experimental drugs being tested in the US and perhaps
elsewhere,
but I haven't heard anything earth-shatteringly new and wonderful yet.
Clinical trials take time.
May be there is a chance not to wait for results but be part of the testing.

Hello Jürgen,
Thank you for clarifying.
Clinical trials (I think) are all here.
http://clinicaltrials.gov/
Search using liver, Germany and hepatic, Germany
If you find nothing (I didn't), ask the doctor about clinical trials

Quote:
[...]
If the doctor's said nothing more can be done, we have to accept it.
That is true and i will do so if i do not find anything else worth to be
evaluated.

I have to ask you. Where's the mets? (where has it spread to?)

and what treatments has she had before.
First line treatment: X number of courses
Second line treatment: X number of courses
etc.
Thank you,
J
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Jürgen Schmitz
medicine forum beginner


Joined: 09 Jun 2005
Posts: 3

PostPosted: Tue Jun 14, 2005 7:50 am    Post subject: Re: new approaches for hepatic cancer? Reply with quote

Quote:
http://clinicaltrials.gov/
I have to ask you. Where's the mets? (where has it spread to?)
and what treatments has she had before.
First line treatment: X number of courses
Second line treatment: X number of courses
Thank you so far,

I do not have exact figures and have to check with the doctor. This will
take a littel time. I will reply when i have more info.

Tanks, Jürgen
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J
medicine forum addict


Joined: 07 May 2005
Posts: 93

PostPosted: Wed Jun 15, 2005 8:09 pm    Post subject: Re: new approaches for hepatic cancer? Reply with quote

"Jürgen Schmitz" wrote:

Quote:
http://clinicaltrials.gov/
I have to ask you. Where's the mets? (where has it spread to?)
and what treatments has she had before.
First line treatment: X number of courses
Second line treatment: X number of courses
Thank you so far,
I do not have exact figures and have to check with the doctor. This will
take a littel time. I will reply when i have more info.

Tanks, Jürgen

Jurgen, perhaps just the names of the first and second line treatments.
And where the cancer has spread to.
Thanks
J
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