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Ibuprofen
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Steven
medicine forum beginner


Joined: 17 Jul 2006
Posts: 3

PostPosted: Mon Jul 17, 2006 2:52 am    Post subject: Ibuprofen Reply with quote

When I take an Advil, I notice a significant reduction in my urinary output.
I have no known renal problems. Should I be concerned about this, is it
safe for me to use?
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Dr. Wayne Simon
medicine forum Guru Wannabe


Joined: 30 Apr 2005
Posts: 111

PostPosted: Mon Jul 17, 2006 4:51 am    Post subject: Re: Ibuprofen Reply with quote

"Steven" <@comcast.net> wrote in message
news:Wq2dnRzoksTEZifZnZ2dnUVZ_uWdnZ2d@comcast.com...
Quote:
When I take an Advil, I notice a significant reduction in my urinary
output.
I have no known renal problems. Should I be concerned about this, is it
safe for me to use?
Some folks have kidneys that are more dependent on the prostaglandin
function. If your kidneys are highly dependent on the functioning of your
prostaglandins, than ibuprofen may have a negative effect on renal
function. Depending on whether you need to take this medication or not, it
might be wise to see your physician for an educated benefit risk analysis
on your medication regimen.
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Steven
medicine forum beginner


Joined: 17 Jul 2006
Posts: 3

PostPosted: Tue Jul 18, 2006 3:07 am    Post subject: Re: Ibuprofen Reply with quote

"> Dr. Wayne Simon" <wayne.simon@comcast.net> wrote in
Quote:
message news:xs-dnYDERsLRiibZnZ2dnUVZ_sOdnZ2d@comcast.com...

"Steven" <@comcast.net> wrote in message
news:Wq2dnRzoksTEZifZnZ2dnUVZ_uWdnZ2d@comcast.com...
When I take an Advil, I notice a significant reduction in my urinary
output.
I have no known renal problems. Should I be concerned about this, is it
safe for me to use?

Some folks have kidneys that are more dependent on the prostaglandin
function. If your kidneys are highly dependent on the functioning of your
prostaglandins, than ibuprofen may have a negative effect on renal
function. Depending on whether you need to take this medication or not,
it might be wise to see your physician for an educated benefit risk
analysis on your medication regimen.

Thanks for the reply. Are there any OTC pain relievers that don't interfere
with prostaglandin synthesis?
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Dr. Wayne Simon
medicine forum Guru Wannabe


Joined: 30 Apr 2005
Posts: 111

PostPosted: Tue Jul 18, 2006 5:13 am    Post subject: Re: Ibuprofen Reply with quote

"Steven" <@comcast.net> wrote in message
news:EZ6dndlS-9-LyCHZnZ2dnUVZ_rudnZ2d@comcast.com...
Quote:

"> Dr. Wayne Simon" <wayne.simon@comcast.net> wrote in
message news:xs-dnYDERsLRiibZnZ2dnUVZ_sOdnZ2d@comcast.com...

"Steven" <@comcast.net> wrote in message
news:Wq2dnRzoksTEZifZnZ2dnUVZ_uWdnZ2d@comcast.com...
When I take an Advil, I notice a significant reduction in my urinary
output.
I have no known renal problems. Should I be concerned about this, is it
safe for me to use?

Some folks have kidneys that are more dependent on the prostaglandin
function. If your kidneys are highly dependent on the functioning of
your prostaglandins, than ibuprofen may have a negative effect on renal
function. Depending on whether you need to take this medication or not,
it might be wise to see your physician for an educated benefit risk
analysis on your medication regimen.

Thanks for the reply. Are there any OTC pain relievers that don't
interfere
with prostaglandin synthesis?

Acetaminophen (paracetamol) is a non anti inflammatory pain reliever that
only blocks prostaglandins in central tissues and not in the kidneys. But
tylenol does in high dose cause liver problems. In regular doses that
should not be a problem.
Quote:

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Steven
medicine forum beginner


Joined: 17 Jul 2006
Posts: 3

PostPosted: Tue Jul 18, 2006 4:28 pm    Post subject: Re: Ibuprofen Reply with quote

Quote:
"Steven"

When I take an Advil, I notice a significant reduction in my urinary
output. I have no known renal problems. Should I be concerned about this,
is it safe for me to use?


"Dr. Wayne Simon"
Some folks have kidneys that are more dependent on the prostaglandin
function. If your kidneys are highly dependent on the functioning of
your prostaglandins, than ibuprofen may have a negative effect on renal
function. Depending on whether you need to take this medication or not,
it might be wise to see your physician for an educated benefit risk
analysis on your medication regimen.


"Steven"
Thanks for the reply. Are there any OTC pain relievers that don't
interfere with prostaglandin synthesis?


"Dr. Wayne Simon" Acetaminophen (paracetamol) is a non anti inflammatory
pain reliever that only blocks prostaglandins in central tissues and not
in the kidneys. But tylenol does in high dose cause liver problems. In
regular doses that should not be a problem.


"Steven"


I would use Acetaminophen for a headache, fever or flu symptoms,

but for muscle ache, back pain or other inflammatory aliments

I would need an NSAID. The question now is if I use

ibuprofen occasionally am I causing renal damage?
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