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Cholesterol drugs may treat hepatitis C
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listener
medicine forum Guru


Joined: 05 May 2005
Posts: 617

PostPosted: Fri Jul 07, 2006 10:39 pm    Post subject: Cholesterol drugs may treat hepatitis C Reply with quote

WASHINGTON (Reuters) - Cholesterol drugs called statins may help treat
hepatitis C infections, Japanese researchers reported on Friday.

Tests in lab dishes suggest that some statin drugs may help stop the
hepatitis C virus from replicating, they wrote in the journal Hepatology,
published by the American Association for the Study of Liver Diseases.

An estimated 170 million people worldwide are infected with the hepatitis
C virus. The standard treatment is a combination therapy of interferon
and ribavirin but it only helps about 55 percent of patients.

The rest risk progression to cirrhosis and liver cancer.

Masanori Ikeda of Okayama University in Japan and colleagues tested
several statin drugs against the virus in lab dishes.

All the drugs except pravastatin interfered with the virus to some
degree. Fluvastatin, sold by Novartis under the name Lescol, had the
strongest effect, they reported.

It may be that certain proteins are required for the hepatitis C virus to
replicate and that some statins block the action of these proteins, the
researchers said.

They tested the statins along with interferon, and found each worked even
better when combined with the second drug.

"We clearly demonstrated that co-treatment of interferon and fluvastatin
was an overwhelmingly effective treatment," the researchers wrote.

Statins -- which include Pfizer Inc.'s $10 billion-a-year Lipitor,
Bristol-Myers Squibb Co.'s Pravachol and Merck and Co. Inc.'s Zocor --
are the world's best-selling drugs, taken by millions to reduce the risk
of heart attack.

But they appear to affect many biological processes. An expert proposed
last month that they may affect influenza viruses, including bird flu,
and other research has shown they reduce the risk of cataracts.

Generic statins are available in many countries and have become
increasingly inexpensive.

###


Must be more of that "pharma-whore researcher worldwide conspiracy"
stuff.

That said, Hep C is a escalating epidemic and any breakthroughs in
treatment are sorely needed (although it's a long way from a lab dish to
a human...).

L.
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William Wagner
medicine forum Guru


Joined: 29 Apr 2005
Posts: 809

PostPosted: Fri Jul 07, 2006 11:09 pm    Post subject: Re: Cholesterol drugs may treat hepatitis C Reply with quote

In article <Xns97F9BDD0D915Fsome1outthere@198.186.190.224>,
listener <listener@nospam.net> wrote:

Quote:
WASHINGTON (Reuters) - Cholesterol drugs called statins may help treat
hepatitis C infections, Japanese researchers reported on Friday.

Tests in lab dishes suggest that some statin drugs may help stop the
hepatitis C virus from replicating, they wrote in the journal Hepatology,
published by the American Association for the Study of Liver Diseases.

An estimated 170 million people worldwide are infected with the hepatitis
C virus. The standard treatment is a combination therapy of interferon
and ribavirin but it only helps about 55 percent of patients.

The rest risk progression to cirrhosis and liver cancer.

Masanori Ikeda of Okayama University in Japan and colleagues tested
several statin drugs against the virus in lab dishes.

All the drugs except pravastatin interfered with the virus to some
degree. Fluvastatin, sold by Novartis under the name Lescol, had the
strongest effect, they reported.

It may be that certain proteins are required for the hepatitis C virus to
replicate and that some statins block the action of these proteins, the
researchers said.

They tested the statins along with interferon, and found each worked even
better when combined with the second drug.

"We clearly demonstrated that co-treatment of interferon and fluvastatin
was an overwhelmingly effective treatment," the researchers wrote.

Statins -- which include Pfizer Inc.'s $10 billion-a-year Lipitor,
Bristol-Myers Squibb Co.'s Pravachol and Merck and Co. Inc.'s Zocor --
are the world's best-selling drugs, taken by millions to reduce the risk
of heart attack.

But they appear to affect many biological processes. An expert proposed
last month that they may affect influenza viruses, including bird flu,
and other research has shown they reduce the risk of cataracts.

Generic statins are available in many countries and have become
increasingly inexpensive.

###


Must be more of that "pharma-whore researcher worldwide conspiracy"
stuff.

That said, Hep C is a escalating epidemic and any breakthroughs in
treatment are sorely needed (although it's a long way from a lab dish to
a human...).

L.

Yet another side effect. Cures every thing except reduced Co-Enzyme
Q10.

Bill

--
S Jersey USA Zone 5 Shade
This article is posted under fair use rules in accordance with
Title 17 U.S.C. Section 107, and is strictly for the educational
and informative purposes. This material is distributed without profit.
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listener
medicine forum Guru


Joined: 05 May 2005
Posts: 617

PostPosted: Sat Jul 08, 2006 4:21 am    Post subject: Re: Cholesterol drugs may treat hepatitis C Reply with quote

William Wagner <not-to-here-williamwag@gmail.com> wrote in news:not-to-
here-williamwag-2329B3.19093607072006@sn-indi.vsrv-sjc.supernews.net:

Quote:
In article <Xns97F9BDD0D915Fsome1outthere@198.186.190.224>,
listener <listener@nospam.net> wrote:

WASHINGTON (Reuters) - Cholesterol drugs called statins may help treat
hepatitis C infections, Japanese researchers reported on Friday.

Tests in lab dishes suggest that some statin drugs may help stop the
hepatitis C virus from replicating, they wrote in the journal
Hepatology,
published by the American Association for the Study of Liver Diseases.

An estimated 170 million people worldwide are infected with the
hepatitis
C virus. The standard treatment is a combination therapy of interferon
and ribavirin but it only helps about 55 percent of patients.

The rest risk progression to cirrhosis and liver cancer.

Masanori Ikeda of Okayama University in Japan and colleagues tested
several statin drugs against the virus in lab dishes.

All the drugs except pravastatin interfered with the virus to some
degree. Fluvastatin, sold by Novartis under the name Lescol, had the
strongest effect, they reported.

It may be that certain proteins are required for the hepatitis C virus
to
replicate and that some statins block the action of these proteins,
the
researchers said.

They tested the statins along with interferon, and found each worked
even
better when combined with the second drug.

"We clearly demonstrated that co-treatment of interferon and
fluvastatin
was an overwhelmingly effective treatment," the researchers wrote.

Statins -- which include Pfizer Inc.'s $10 billion-a-year
Lipitor,
Bristol-Myers Squibb Co.'s Pravachol and Merck and Co. Inc.'s Zocor --
are the world's best-selling drugs, taken by millions to reduce the
risk
of heart attack.

But they appear to affect many biological processes. An expert
proposed
last month that they may affect influenza viruses, including bird flu,
and other research has shown they reduce the risk of cataracts.

Generic statins are available in many countries and have become
increasingly inexpensive.

###


Must be more of that "pharma-whore researcher worldwide conspiracy"
stuff.

That said, Hep C is a escalating epidemic and any breakthroughs in
treatment are sorely needed (although it's a long way from a lab dish
to
a human...).

L.

Yet another side effect. Cures every thing except reduced Co-Enzyme
Q10.

Bill


I don't think that any of the (pro-statin) articles I post actually tout
statins as a "cure" for anything - just that they *may* be useful in
treatment. Then again, they may not. I certainly don't view them as a
cure. That's your word.

L.
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William Wagner
medicine forum Guru


Joined: 29 Apr 2005
Posts: 809

PostPosted: Sat Jul 08, 2006 11:47 am    Post subject: Re: Cholesterol drugs may treat hepatitis C Reply with quote

Thought L may find this of interest.

Bill
.................................


1: J Am Coll Cardiol. 2006 Jun 20;47(12):2554-60. Epub 2006 May 2.
Related Articles, Links
 
Reduction of morbidity and mortality by statins, angiotensin-converting
enzyme inhibitors, and angiotensin receptor blockers in patients with
chronic obstructive pulmonary disease.

Mancini GB, Etminan M, Zhang B, Levesque LE, FitzGerald JM, Brophy JM.

Division of Cardiology, Vancouver Hospital, Jack Bell Research Centre,
University of British Columbia, Vancouver, British Columbia, Canada.
mancini@interchange.ubc.ca

OBJECTIVES: The purpose of this study was to determine if statins
(hydroxymethylglutaryl CoA reductase inhibitors [HMG-CoA]),
angiotensin-converting enzyme (ACE) inhibitors, and angiotensin receptor
blockers (ARBs) reduce cardiovascular (CV) events and pulmonary
morbidity in chronic obstructive pulmonary disease (COPD) patients.
BACKGROUND: Few current COPD therapies alter prognosis. Although
statins, ACE inhibitors, and ARBs improve outcomes in CV populations,
their benefits in COPD patients both with and without concomitant heart
disease has not previously been studied. METHODS: A time-matched nested
case-control study of two population-based retrospective cohorts was
undertaken: 1) COPD patients having undergone coronary revascularization
(high CV risk cohort); and 2) COPD patients without previous myocardial
infarction (MI) and newly treated with nonsteroidal anti-inflammatory
drugs (low CV risk cohort). Prespecified outcomes were COPD
hospitalization, MI, and total mortality. RESULTS: These drugs reduced
both CV and pulmonary outcomes, with the largest benefits occurring with
the combination of statins and either ACE inhibitors or ARBs. This
combination was associated with a reduction in COPD hospitalization
(risk ratio [RR] 0.66, 95% confidence interval [CI] 0.51 to 0.85) and
total mortality (RR 0.42, 95% CI 0.33 to 0.52) not only in the high CV
risk cohort but also in the low CV risk cohort (RR 0.77, 95% CI 0.67 to
0.87, and RR 0.36, 95% CI 0.28 to 0.45, respectively). The combination
also reduced MI in the high CV risk cohort (RR 0.39, 95% CI 0.31 to
0.49). Benefits were similar when steroid users were included.
CONCLUSIONS: These agents may have dual cardiopulmonary protective
properties, thereby substantially altering prognosis of patients with
COPD. These findings need confirmation in randomized clinical trials.

PMID: 16781387 [PubMed - in process]

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David Rind
medicine forum Guru Wannabe


Joined: 02 May 2005
Posts: 205

PostPosted: Sat Jul 08, 2006 1:03 pm    Post subject: Re: Cholesterol drugs may treat hepatitis C Reply with quote

listener wrote:
Quote:
I don't think that any of the (pro-statin) articles I post actually tout
statins as a "cure" for anything - just that they *may* be useful in
treatment. Then again, they may not. I certainly don't view them as a
cure. That's your word.

L.

At the same time, it's worth realizing that most of these supposed
statin benefits are unlikely to pan out. The evidence on avian flu and
hep C comes from bench research not patient studies.

When side benefits suggested in observational studies (like decreased
rates of cancer) have been looked for in the randomized trials they have
not been seen. The observational studies on cataracts mostly have shown
no effect -- I have no idea why JAMA decided to publish the single
article showing decreased rates of cataract given the negative studies
already published elsewhere.

Unlike the impression many readers of smc might get, statins are
spectacular drugs that have been proven in randomized trials to have
important effects in reducing mortality and cardiovascular events in
people with cardiovascular disease.

But it's not worth spending much time on every observational study or
bit of bench research someone publishes showing this or that side
benefit with statins -- either these results should be noticeable in the
huge randomized trials already published, or, if we're talking about
treatment of uncommon diseases, will require their own randomized trials.

--
David Rind
drind@caregroup.harvard.edu
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Susan
medicine forum Guru


Joined: 05 May 2005
Posts: 932

PostPosted: Sat Jul 08, 2006 4:05 pm    Post subject: Re: Cholesterol drugs may treat hepatitis C Reply with quote

x-no-archive: yes

listener wrote:

Quote:
I don't think that any of the (pro-statin) articles I post actually tout
statins as a "cure" for anything - just that they *may* be useful in
treatment. Then again, they may not. I certainly don't view them as a
cure. That's your word.

L.

You're a transparent shill.

I'm not interested til they prove it'll detail my car while I sleep.

Susan
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William Wagner
medicine forum Guru


Joined: 29 Apr 2005
Posts: 809

PostPosted: Sat Jul 08, 2006 4:50 pm    Post subject: Re: Cholesterol drugs may treat hepatitis C Reply with quote

In article <Xns97FA39876397some1outthere@198.186.190.224>,
listener <listener@nospam.net> wrote:

Quote:
William Wagner <not-to-here-williamwag@gmail.com> wrote in news:not-to-
here-williamwag-2329B3.19093607072006@sn-indi.vsrv-sjc.supernews.net:

In article <Xns97F9BDD0D915Fsome1outthere@198.186.190.224>,
listener <listener@nospam.net> wrote:

WASHINGTON (Reuters) - Cholesterol drugs called statins may help treat
hepatitis C infections, Japanese researchers reported on Friday.

Tests in lab dishes suggest that some statin drugs may help stop the
hepatitis C virus from replicating, they wrote in the journal
Hepatology,
published by the American Association for the Study of Liver Diseases.

An estimated 170 million people worldwide are infected with the
hepatitis
C virus. The standard treatment is a combination therapy of interferon
and ribavirin but it only helps about 55 percent of patients.

The rest risk progression to cirrhosis and liver cancer.

Masanori Ikeda of Okayama University in Japan and colleagues tested
several statin drugs against the virus in lab dishes.

All the drugs except pravastatin interfered with the virus to some
degree. Fluvastatin, sold by Novartis under the name Lescol, had the
strongest effect, they reported.

It may be that certain proteins are required for the hepatitis C virus
to
replicate and that some statins block the action of these proteins,
the
researchers said.

They tested the statins along with interferon, and found each worked
even
better when combined with the second drug.

"We clearly demonstrated that co-treatment of interferon and
fluvastatin
was an overwhelmingly effective treatment," the researchers wrote.

Statins -- which include Pfizer Inc.'s $10 billion-a-year
Lipitor,
Bristol-Myers Squibb Co.'s Pravachol and Merck and Co. Inc.'s Zocor --
are the world's best-selling drugs, taken by millions to reduce the
risk
of heart attack.

But they appear to affect many biological processes. An expert
proposed
last month that they may affect influenza viruses, including bird flu,
and other research has shown they reduce the risk of cataracts.

Generic statins are available in many countries and have become
increasingly inexpensive.

###


Must be more of that "pharma-whore researcher worldwide conspiracy"
stuff.

That said, Hep C is a escalating epidemic and any breakthroughs in
treatment are sorely needed (although it's a long way from a lab dish
to
a human...).

L.

Yet another side effect. Cures every thing except reduced Co-Enzyme
Q10.

Bill


I don't think that any of the (pro-statin) articles I post actually tout
statins as a "cure" for anything - just that they *may* be useful in
treatment. Then again, they may not. I certainly don't view them as a
cure. That's your word.

L.

May is a wonderful word. May may be transposed to could . I think it
means ambiguity.


may 1 |m?| |me?| |me?|
modal verb ( 3rd sing. present may |me?|; past might |m?t| |ma?t| |m??t|)
1 expressing possibility : that may be true | he may well win.
€ used when admitting that something is so before making another, more
important point : they may have been old-fashioned, but they were
excellent teachers.
2 expressing permission : you may use a sling if you wish | may I ask a
few questions?
3 expressing a wish or hope : may she rest in peace.
PHRASES
be that as it may despite that; nevertheless.
may as well another way of saying might as well (see might 1 ).
ORIGIN Old English mæg, of Germanic origin, from a base meaning Œhave
power¹ ; related to Dutch mogen and German mögen, also to main 1 and
might 2 .

Ambiguity |?ambi?gyo?-it?| |?ømb??gj?w?di| |amb??gju??ti|
noun ( pl. -ties)
uncertainty or inexactness of meaning in language : we can detect no
ambiguity in this section of the Act | ambiguities in such questions are
potentially very dangerous.
€ a lack of decisiveness or commitment resulting from a failure to make
a choice between alternatives : the film is fraught with moral ambiguity.
ORIGIN late Middle English : from Old French ambiguite or Latin
ambiguitas, from ambiguus Œdoubtful¹ (see ambiguous ).



Thesaurus

ambiguity
noun
the ambiguity of the rule made it impossible to follow vagueness,
obscurity, abstruseness, doubtfulness, uncertainty; formal dubiety;
ambivalence, equivocation, double meaning.

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William Wagner
medicine forum Guru


Joined: 29 Apr 2005
Posts: 809

PostPosted: Sat Jul 08, 2006 6:03 pm    Post subject: Re: Cholesterol drugs may treat hepatitis C Reply with quote

In article <e8oag6$9oi$1@reader2.panix.com>,
David Rind <drind@caregroup.harvard.edu> wrote:


Quote:
Unlike the impression many readers of smc might get, statins are
spectacular drugs that have been proven in randomized trials to have
important effects in reducing mortality and cardiovascular events in
people with cardiovascular disease.

Ok for us folks where statins cause damage. I'd like to know why
lowering my total is a good thing ?

If I go to http://www.mayoclinic.com/health/heart-disease-risk/HB00047
there is no mention of HDL and there is no longevity benefit. LDL size
too expensive for me I'm calculated.

What I am is suggesting that cholesterol is mute issue and the "Cure"
is flawed in that it causes harm. CoQ-10 issues.

Harvard my ass.

Bill

--
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This article is posted under fair use rules in accordance with
Title 17 U.S.C. Section 107, and is strictly for the educational
and informative purposes. This material is distributed without profit.
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David Rind
medicine forum Guru Wannabe


Joined: 02 May 2005
Posts: 205

PostPosted: Sat Jul 08, 2006 6:57 pm    Post subject: Re: Cholesterol drugs may treat hepatitis C Reply with quote

William Wagner wrote:
Quote:
In article <e8oag6$9oi$1@reader2.panix.com>,
David Rind <drind@caregroup.harvard.edu> wrote:



Unlike the impression many readers of smc might get, statins are
spectacular drugs that have been proven in randomized trials to have
important effects in reducing mortality and cardiovascular events in
people with cardiovascular disease.


Ok for us folks where statins cause damage. I'd like to know why
lowering my total is a good thing ?

If I go to http://www.mayoclinic.com/health/heart-disease-risk/HB00047
there is no mention of HDL and there is no longevity benefit. LDL size
too expensive for me I'm calculated.

What I am is suggesting that cholesterol is mute issue and the "Cure"
is flawed in that it causes harm. CoQ-10 issues.

Harvard my ass.

Bill

Thank you for that coherent post. If there's an actual comment or
question there, you might try again.

--
David Rind
drind@caregroup.harvard.edu
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William Wagner
medicine forum Guru


Joined: 29 Apr 2005
Posts: 809

PostPosted: Sat Jul 08, 2006 7:17 pm    Post subject: Re: Cholesterol drugs may treat hepatitis C Reply with quote

In article <e8ov7k$lh6$1@reader2.panix.com>,
David Rind <drind@caregroup.harvard.edu> wrote:

Quote:
William Wagner wrote:
In article <e8oag6$9oi$1@reader2.panix.com>,
David Rind <drind@caregroup.harvard.edu> wrote:



Unlike the impression many readers of smc might get, statins are
spectacular drugs that have been proven in randomized trials to have
important effects in reducing mortality and cardiovascular events in
people with cardiovascular disease.


A> > Ok for us folks where statins cause damage. I'd like to know why
lowering my total is a good thing ?

B> > If I go to

http://www.mayoclinic.com/health/heart-disease-risk/HB00047
Quote:
there is no mention of HDL and there is no longevity benefit. LDL size
too expensive for me I'm calculated.

C> > What I am is suggesting that cholesterol is mute issue and the

"Cure"
Quote:
is flawed in that it causes harm. CoQ-10 issues.

Harvard my ass.

Bill

Thank you for that coherent post. If there's an actual comment or
question there, you might try again.

A & B are are questions.
C is a statement.

Simple enough?

Coherent... please do not try to insult me.

Bill

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David Rind
medicine forum Guru Wannabe


Joined: 02 May 2005
Posts: 205

PostPosted: Sat Jul 08, 2006 8:09 pm    Post subject: Re: Cholesterol drugs may treat hepatitis C Reply with quote

William Wagner wrote:

Quote:
A> > Ok for us folks where statins cause damage. I'd like to know why

lowering my total is a good thing ?

I haven't a clue whether statins are a good thing for you knowing
nothing about you or your medical history. However, for the average
person with known cardiovascular disease statins will decrease
cardiovascular events by about 30% and mortality by close to 20%.
Statins don't cause serious enough side effects in most patients to
outweigh those sorts of benefits.

Quote:


B> > If I go to
http://www.mayoclinic.com/health/heart-disease-risk/HB00047

there is no mention of HDL and there is no longevity benefit. LDL size
too expensive for me I'm calculated.

When I go there, I see a cardiac risk calculator. I'm not sure what that
has to do with the sentence you wrote above or what your sentence means.

For what it's worth, this risk calculator does not apply to people with
known cardiovascular disease (i.e. the people I was saying get clear
benefits from statins).

Quote:


C> > What I am is suggesting that cholesterol is mute issue and the
"Cure"

is flawed in that it causes harm. CoQ-10 issues.

Okay, since C is a "coherent" comment and not a question, what do you
think the word "mute" means? Also, when has anyone ever suggested that
statins are a "cure"? They are a drug taken chronically to treat a
chronic condition, and like all drugs they have benefits and harms. In
most patients with cardiovascular disease, the benefits far outweigh the
harms.

Quote:

Harvard my ass.

Coherent... please do not try to insult me.

Gee, you think that first sentence from you might be an insult? Do you
think my pointing out the incoherence of your post is harsher than that,
or do you figure on Usenet you get to make nasty comments but no one
should respond?

--
David Rind
drind@caregroup.harvard.edu
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listener
medicine forum Guru


Joined: 05 May 2005
Posts: 617

PostPosted: Sat Jul 08, 2006 8:15 pm    Post subject: Re: Cholesterol drugs may treat hepatitis C Reply with quote

William Wagner <not-to-here-williamwag@gmail.com> wrote in news:not-to-
here-williamwag-28C6BF.12501008072006@sn-indi.vsrv-sjc.supernews.net:

Quote:
May is a wonderful word. May may be transposed to could . I think it
means ambiguity.


[snip silly english lesson]


Hey, you wanna talk about statins as "cures" that's your perogative.

L.
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listener
medicine forum Guru


Joined: 05 May 2005
Posts: 617

PostPosted: Sat Jul 08, 2006 8:21 pm    Post subject: Re: Cholesterol drugs may treat hepatitis C Reply with quote

Susan <nevermind@nomail.com> wrote in news:4ha3evF1qb54cU2@individual.net:

Quote:
x-no-archive: yes

listener wrote:

I don't think that any of the (pro-statin) articles I post actually tout
statins as a "cure" for anything - just that they *may* be useful in
treatment. Then again, they may not. I certainly don't view them as a
cure. That's your word.

L.

You're a transparent shill.

I'm not interested til they prove it'll detail my car while I sleep.

Susan

And you are...ah....just plain old transparent? Since I have no connection
whatsoever to doctors or researchers or phama (not even related to any) I'm
not sure what or who I'm a shill for? That notion is only in your own mind.

Yeh, I know - you've used that cute line before, "detail my
car"..ha...ha..you made a funny!

L.
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William Wagner
medicine forum Guru


Joined: 29 Apr 2005
Posts: 809

PostPosted: Sat Jul 08, 2006 8:34 pm    Post subject: Re: Cholesterol drugs may treat hepatitis C Reply with quote

In article <e8p3e6$oud$1@reader2.panix.com>,
David Rind <drind@caregroup.harvard.edu> wrote:


Quote:

B> > If I go to
http://www.mayoclinic.com/health/heart-disease-risk/HB00047

there is no mention of HDL and there is no longevity benefit. LDL size
too expensive for me I'm calculated.

When I go there, I see a cardiac risk calculator. I'm not sure what that
has to do with the sentence you wrote above or what your sentence means.

For what it's worth, this risk calculator does not apply to people with
known cardiovascular disease (i.e. the people I was saying get clear
benefits from statins).

see http://www.ti.ubc.ca/pages/letter.html 48 & 49
Quote:



C> > What I am is suggesting that cholesterol is mute issue and the
"Cure"

is flawed in that it causes harm. CoQ-10 issues.

Okay, since C is a "coherent" comment and not a question, what do you
think the word "mute" means? Also, when has anyone ever suggested that
statins are a "cure"? They are a drug taken chronically to treat a
chronic condition, and like all drugs they have benefits and harms. In
most patients with cardiovascular disease, the benefits far outweigh the
harms.


Mute means it should be common knowledge everywhere but is not
available readably. Many folks never heard of CoQ-10 yet no TV
Crestor ad speaks of it. That is MUTE.
Quote:

Harvard my ass.

Coherent... please do not try to insult me.

Gee, you think that first sentence from you might be an insult? Do you
think my pointing out the incoherence of your post is harsher than that,
or do you figure on Usenet you get to make nasty comments but no one
should respond?

Harvard is not you but coherent was aimed at me. Harvard is a moniker
to give validity to you posts. Just as Jim with the MIT address.
Post as folks and I'm sure you will be welcomed or scorned by your words.
Hide like L and be treated as such.


Bill

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William Wagner
medicine forum Guru


Joined: 29 Apr 2005
Posts: 809

PostPosted: Sat Jul 08, 2006 8:48 pm    Post subject: Re: Cholesterol drugs may treat hepatitis C Reply with quote

In article <e8p3e6$oud$1@reader2.panix.com>,
David Rind <drind@caregroup.harvard.edu> wrote:

Quote:
William Wagner wrote:

A> > Ok for us folks where statins cause damage. I'd like to know why

lowering my total is a good thing ?

I haven't a clue whether statins are a good thing for you knowing
nothing about you or your medical history. However, for the average
person with known cardiovascular disease statins will decrease
cardiovascular events by about 30% and mortality by close to 20%.
Statins don't cause serious enough side effects in most patients to
outweigh those sorts of benefits.



B> > If I go to
http://www.mayoclinic.com/health/heart-disease-risk/HB00047

there is no mention of HDL and there is no longevity benefit. LDL size
too expensive for me I'm calculated.

When I go there, I see a cardiac risk calculator. I'm not sure what that
has to do with the sentence you wrote above or what your sentence means.

For what it's worth, this risk calculator does not apply to people with
known cardiovascular disease (i.e. the people I was saying get clear
benefits from statins).



C> > What I am is suggesting that cholesterol is mute issue and the
"Cure"

is flawed in that it causes harm. CoQ-10 issues.

Okay, since C is a "coherent" comment and not a question, what do you
think the word "mute" means? Also, when has anyone ever suggested that
statins are a "cure"? They are a drug taken chronically to treat a
chronic condition, and like all drugs they have benefits and harms. In
most patients with cardiovascular disease, the benefits far outweigh the
harms.


Harvard my ass.

Coherent... please do not try to insult me.

Gee, you think that first sentence from you might be an insult? Do you
think my pointing out the incoherence of your post is harsher than that,
or do you figure on Usenet you get to make nasty comments but no one
should respond?

I'm sorry !

I always try to write like I'm addressing my best friend. My best
friends and I have exchanged curse words but this medium gives me many
opportunities for mistakes and a few glimpses of truth or retraction.
Still a pain in the arse.

Bill

Hope Yale beats Harvard if that is coherent..

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