| Author |
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Susan
medicine forum Guru
Joined: 05 May 2005
Posts: 932
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 Posted: Wed Jun 01, 2005 5:09 pm Post subject:
Higher cholesterol in the elderly associated with lower dementia risk
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x-no-archive: yes
http://www.medscape.com/viewarticle/505777_print
"The team observed an association between increasing cholesterol levels
(per mmol/L) at age 70 (hazard ratio [HR] 0.77; p = 0.02) and a lower
risk of dementia between ages 79 and 88 years. Increasing cholesterol
levels at ages 75 (HR 0.70) and 79 (HR 0.73) were also significantly
linked to a reduced dementia risk. No association was found between
triglyceride levels and dementia."
Susan |
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Jim Chinnis
medicine forum Guru
Joined: 30 Apr 2005
Posts: 1030
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| Posted: Wed Jun 01, 2005 6:06 pm Post subject:
Re: Higher cholesterol in the elderly associated with lower dementia risk
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Susan <nevermind@nomail.com> wrote in part:
| Quote: | x-no-archive: yes
http://www.medscape.com/viewarticle/505777_print
"The team observed an association between increasing cholesterol levels
(per mmol/L) at age 70 (hazard ratio [HR] 0.77; p = 0.02) and a lower
risk of dementia between ages 79 and 88 years. Increasing cholesterol
levels at ages 75 (HR 0.70) and 79 (HR 0.73) were also significantly
linked to a reduced dementia risk. No association was found between
triglyceride levels and dementia."
|
The abstract mumbles something about the difference in cholesterol
measurement timing explaining why this study shows an effect in
the opposite direction from the one found for cholesterol levels
in early middle age. My guess is that people who survive very high
cholesterol levels and make it into old age aren't made like most
of the rest of us... Genetics.
(Hey--I know one of the authors...an old buddy of mine. Does that
mean I am too biased to be credible saying anything on this?)
--
Jim Chinnis Warrenton, Virginia, USA |
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Susan
medicine forum Guru
Joined: 05 May 2005
Posts: 932
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| Posted: Wed Jun 01, 2005 6:17 pm Post subject:
Re: Higher cholesterol in the elderly associated with lower dementia risk
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x-no-archive: yes
Jim Chinnis wrote:
| Quote: |
The abstract mumbles something about the difference in cholesterol
measurement timing explaining why this study shows an effect in
the opposite direction from the one found for cholesterol levels
in early middle age. My guess is that people who survive very high
cholesterol levels and make it into old age aren't made like most
of the rest of us... Genetics.
|
That may well be the case; they may have a genetic tendency toward nice,
big fluffy lipid particles that don't oxidize and cause damage.
| Quote: |
(Hey--I know one of the authors...an old buddy of mine. Does that
mean I am too biased to be credible saying anything on this?)
--
Jim Chinnis Warrenton, Virginia, USA
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Nah, that wouldn't do it. Tthe fact that you're a bit of an academic
Pollyanna, *that* could do it. ;-P |
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Jim Chinnis
medicine forum Guru
Joined: 30 Apr 2005
Posts: 1030
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| Posted: Wed Jun 01, 2005 6:21 pm Post subject:
Re: Higher cholesterol in the elderly associated with lower dementia risk
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Susan <nevermind@nomail.com> wrote in part:
| Quote: | x-no-archive: yes
Jim Chinnis wrote:
The abstract mumbles something about the difference in cholesterol
measurement timing explaining why this study shows an effect in
the opposite direction from the one found for cholesterol levels
in early middle age. My guess is that people who survive very high
cholesterol levels and make it into old age aren't made like most
of the rest of us... Genetics.
That may well be the case; they may have a genetic tendency toward nice,
big fluffy lipid particles that don't oxidize and cause damage.
(Hey--I know one of the authors...an old buddy of mine. Does that
mean I am too biased to be credible saying anything on this?)
--
Jim Chinnis Warrenton, Virginia, USA
Nah, that wouldn't do it. Tthe fact that you're a bit of an academic
Pollyanna, *that* could do it. ;-P
|
The only academic job I've ever had was a year-long post-doc. And
that was a lot of years ago.
--
Jim Chinnis Warrenton, Virginia, USA |
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Susan
medicine forum Guru
Joined: 05 May 2005
Posts: 932
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| Posted: Wed Jun 01, 2005 7:00 pm Post subject:
Re: Higher cholesterol in the elderly associated with lower dementia risk
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x-no-archive: yes
Jim Chinnis wrote:
| Quote: | The only academic job I've ever had was a year-long post-doc. And
that was a lot of years ago.
--
Jim Chinnis Warrenton, Virginia, USA
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Okay, but you're still a Pollyanna. ;-)
And you think like an academic, which isn't entirely a bad thing...
Susan |
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William Wagner
medicine forum Guru
Joined: 29 Apr 2005
Posts: 809
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| Posted: Wed Jun 01, 2005 7:22 pm Post subject:
Re: Higher cholesterol in the elderly associated with lower dementia risk
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In article <3g6lvnFasdpbU1@individual.net>,
Susan <nevermind@nomail.com> wrote:
| Quote: | x-no-archive: yes
Jim Chinnis wrote:
The only academic job I've ever had was a year-long post-doc. And
that was a lot of years ago.
--
Jim Chinnis Warrenton, Virginia, USA
Okay, but you're still a Pollyanna. ;-)
And you think like an academic, which isn't entirely a bad thing...
Susan
|
Thinking like an academic is a good thing. However reading /learning
about stuff not assigned is of equal value. If you think this is
nonsense consider sweating a copper pipe yourself vs. getting a plumber
in to do the real work.
Bill who is a Pollyanna too and has be practicing martial arts for
36 years. Go Figure  ) My hands are soft and smooth and I will yield
to let you have your way...perhaps help you .
--
Garden in shade Zone 5 S Jersey USA
Long -75.0246 Lat 39.637876
Enjoy http://terrafly.fiu.edu/ |
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Susan
medicine forum Guru
Joined: 05 May 2005
Posts: 932
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| Posted: Wed Jun 01, 2005 7:26 pm Post subject:
Re: Higher cholesterol in the elderly associated with lower dementia risk
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x-no-archive: yes
William Wagner wrote:
| Quote: | Thinking like an academic is a good thing.
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Yup, mostly.
| Quote: | However reading /learning
about stuff not assigned is of equal value. If you think this is
nonsense consider sweating a copper pipe yourself vs. getting a plumber
in to do the real work.
|
Thanks, but, that sounds like an assignment. :-)
| Quote: |
Bill who is a Pollyanna too and has be practicing martial arts for
36 years. Go Figure ) My hands are soft and smooth and I will yield
to let you have your way...perhaps help you .
|
Susan <whose garden is also mostly in shade in Noo Yawk> |
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Bill
medicine forum Guru
Joined: 06 May 2005
Posts: 849
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| Posted: Wed Jun 01, 2005 10:49 pm Post subject:
Re: Higher cholesterol in the elderly associated with lower dementia risk
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"Susan" <nevermind@nomail.com> wrote in message
news:3g6ffpFaus7cU1@individual.net...
| Quote: | x-no-archive: yes
http://www.medscape.com/viewarticle/505777_print
"The team observed an association between increasing cholesterol levels (per
mmol/L) at age 70 (hazard ratio [HR] 0.77; p = 0.02) and a lower risk of
dementia between ages 79 and 88 years. Increasing cholesterol levels at ages
75 (HR 0.70) and 79 (HR 0.73) were also significantly linked to a reduced
dementia risk. No association was found between triglyceride levels and
dementia."
Susan
|
There is also a question of cause and effect. My mother was overweight in her
early 70s and died at 93 looking like one of those concentration camp figures
you sometimes see on TV, The reason is that over time she ate less and less.
And, at the end, was eating essentially nothing. Her dementia also became
worse over time.
She was not taking any Lipid lowering drugs. I attribute her lack of eating to
dementia.
But things could work the other way too. The evidence seems conflicting.
Bill |
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Bill
medicine forum Guru
Joined: 06 May 2005
Posts: 849
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| Posted: Wed Jun 01, 2005 10:53 pm Post subject:
Re: Higher cholesterol in the elderly associated with lower dementia risk
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"Susan" <nevermind@nomail.com> wrote in message
news:3g6ng7Fan4qbU1@individual.net...
| Quote: | x-no-archive: yes
William Wagner wrote:
Thinking like an academic is a good thing.
Yup, mostly.
However reading /learning about stuff not assigned is of equal value. If
you think this is nonsense consider sweating a copper pipe yourself vs.
getting a plumber in to do the real work.
Thanks, but, that sounds like an assignment. :-)
Bill who is a Pollyanna too and has be practicing martial arts for 36
years. Go Figure ) My hands are soft and smooth and I will yield to
let you have your way...perhaps help you .
Susan <whose garden is also mostly in shade in Noo Yawk
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City or state?
Bill |
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Susan
medicine forum Guru
Joined: 05 May 2005
Posts: 932
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| Posted: Wed Jun 01, 2005 11:10 pm Post subject:
Re: Higher cholesterol in the elderly associated with lower dementia risk
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x-no-archive: yes
Bill wrote:
Lawn Guyland.
Susan |
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Susan
medicine forum Guru
Joined: 05 May 2005
Posts: 932
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| Posted: Wed Jun 01, 2005 11:11 pm Post subject:
Re: Higher cholesterol in the elderly associated with lower dementia risk
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x-no-archive: yes
Bill wrote:
| Quote: | There is also a question of cause and effect. My mother was overweight in her
early 70s and died at 93 looking like one of those concentration camp figures
you sometimes see on TV, The reason is that over time she ate less and less.
And, at the end, was eating essentially nothing. Her dementia also became
worse over time.
She was not taking any Lipid lowering drugs. I attribute her lack of eating to
dementia.
But things could work the other way too. The evidence seems conflicting.
|
Well, yeah. The article only notes an association.
Susan |
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Bill
medicine forum Guru
Joined: 06 May 2005
Posts: 849
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| Posted: Thu Jun 02, 2005 1:50 am Post subject:
Re: Higher cholesterol in the elderly associated with lower dementia risk
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"Susan" <nevermind@nomail.com> wrote in message
news:3g74ksFavencU2@individual.net...
| Quote: | x-no-archive: yes
Bill wrote:
City or state?
Lawn Guyland.
Susan
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Got it. I'm on the mainland.
Bill |
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