Vegetable soup / oxidative stress

ironjustice@aol.com · medicine forum Guru Joined: 28 Apr 2005 Posts: 1522

The Journal of Nutritional Biochemistry
Volume 17, Issue 3 , March 2006, Pages 183-189

doi:10.1016/j.jnutbio.2005.07.001
Copyright © 2006 Elsevier Inc. All rights reserved.
Research article
Mediterranean vegetable soup consumption increases plasma vitamin C and
decreases F2-isoprostanes, prostaglandin E2 and monocyte chemotactic
protein-1 in healthy humans

Concepción Sánchez-Morenoa, b, , , M. Pilar Canob, Begoña de Ancosb,
Lucía Plazab, Begoña Olmedillac, Fernando Granadoc and Antonio
Martína

aNutrition and Neurocognition Laboratory, Jean Mayer USDA-Human
Nutrition Research Center on Aging at Tufts University, Boston, MA
02111, USA
bDepartment of Plant Foods Science and Technology, Instituto del
Frío-CSIC, E-28040 Marid, Spain
cUnit of Vitamins, Section of Nutrition, Clínica Puerta de Hierro,
28035 Madrid, Spain

Available online 15 August 2005.

Abstract
Consumption of fruits and vegetables is associated with a reduced risk
of death from all causes including heart disease and stroke. In this
work, the bioavailability of vitamin C from a Mediterranean vegetable
soup (gazpacho) constituted mainly of tomato, pepper and cucumber, and
its influence on plasma vitamin C, 8-epi-prostaglandin F2a
(8-epi-PGF2a), prostaglandin E2 (PGE2), monocyte chemotactic protein-1
(MCP-1), and the cytokines/tumor necrosis factor-a (TNF-a),
interleukin-1ß (IL-1ß), and IL-6 concentrations in a healthy human
population were assessed. Six men and six women consumed 500 ml of
commercial gazpacho per day for 14 days, corresponding to an intake of
78 mg of ascorbic acid per day. There were no differences (P=.22) in
baseline plasma vitamin C concentrations between the men and women. The
maximum increase (P<.05) in plasma vitamin C occurred 4 h postdose in
both men and women. Vitamin C concentrations were significantly higher
(P<.03) on Days 7 and 14 of the intervention. Baseline concentrations
of uric acid and 8-epi-PGF2a were significantly higher (P=.032) in men
than in women. Baseline concentrations of 8-epi-PGF2a decreased
significantly (P=.05) by Day 14 of the intervention. A significant
inverse correlation was observed between vitamin C and 8-epi-PGF2a
(r=-.415, P=.049). Baseline concentrations of PGF2 and MCP-1 were
significantly higher (P=.025) in men than in women but decreased
significantly (P=.05) by Day 14 of the intervention. No effect on
TNF-a, IL-1ß and IL-6 was observed at Day 14 of the intervention.
Drinking gazpacho (500 ml/day) significantly increases plasma
concentrations of vitamin C and significantly decreases 8-epi-PGF2a,
PGE2 and MCP-1 concentrations in healthy humans.

Keywords: Vegetable soup; Vitamin C; Bioavailability; F2-Isoprostanes;
Uric acid; Cytokines; Inflammatory markers

Supported in part by the Coordinated Grant CAM 07G/0040/2000-CAM
07G/0041/2000 (Comunidad Autónoma de Madrid), the Grant
AGL2002-04059-C02-02 (Ministry of Science and Technology, Madrid,
Spain) (MPC); a Fulbright/Ministry of Education, Culture and Sports
Award for Postdoctoral Research in the United States of America,
Visiting Scholar Program, Commission for Cultural, Educational and
Scientific Exchange between the United States of America and Spain, and
a Ramón y Cajal Research Contract (Ministry of Science and Technology,
Madrid, Spain) (CS-M). An earlier version of this article was presented
at Experimental Biology 2004, Washington DC, USA, April 2004.
Corresponding author. Department of Plant Foods Science and Technology,
Instituto del Frío, Consejo Superior de Investigaciones Científicas
(CSIC), C/José Antonio Novais 10, Ciudad Universitaria, E-28040
Madrid, Spain. Tel.: +34 91 549 23 00, +34 91 544 56 07; fax: +34 91
549 36 27.

The Journal of Nutritional Biochemistry
Volume 17, Issue 3 , March 2006, Pages 183-189

Who loves ya.
Tom

Jesus Was A Vegetarian!
http://jesuswasavegetarian.7h.com

Man Is A Herbivore!
http://pages.ivillage.com/ironjustice/manisaherbivore

DEAD PEOPLE WALKING
http://pages.ivillage.com/ironjustice/deadpeoplewalking

jaym1212 · medicine forum addict Joined: 10 May 2005 Posts: 79

Sylv · medicine forum addict Joined: 27 Aug 2005 Posts: 86

Wake up feeling lousy, but Tommy Boy nails it again!

Heat DESTROYS Vitamin C, so ya better make it a cold soup to get any
benefits of Vitamin C.

Maybe I missed it, genius, but I saw NO mention of temperature in this
article. . .

Most from round here eat HOT soup; something to take the chill out of
winter days.

I seem to remember this info posted. . .oh, about a year ago. Can't
blame Tommy with being current, now can we? Or giving out ALL the
information!

Sylvia (still snickering)

pellmellwillynilly@hotmai · medicine forum addict Joined: 02 Oct 2005 Posts: 53

I'm no fan of Ironjustice, but to his credit, the study *was* about
gazpacho -- a very world-renowned chilled soup made with raw
ingredients.

Sylv wrote:

Rob Duncan · medicine forum beginner Joined: 31 Aug 2005 Posts: 16

The value of gespacho is old news. This study is a repeat. And cold soup
sucks anyways, so why bother posting it...?

Rob

<ironjustice@aol.com> wrote in message
news:1141062643.211245.314420@v46g2000cwv.googlegroups.com...

The Journal of Nutritional Biochemistry
Volume 17, Issue 3 , March 2006, Pages 183-189

doi:10.1016/j.jnutbio.2005.07.001
Copyright © 2006 Elsevier Inc. All rights reserved.
Research article
Mediterranean vegetable soup consumption increases plasma vitamin C and
decreases F2-isoprostanes, prostaglandin E2 and monocyte chemotactic
protein-1 in healthy humans

Concepción Sánchez-Morenoa, b, , , M. Pilar Canob, Begoña de Ancosb,
Lucía Plazab, Begoña Olmedillac, Fernando Granadoc and Antonio
Martína

aNutrition and Neurocognition Laboratory, Jean Mayer USDA-Human
Nutrition Research Center on Aging at Tufts University, Boston, MA
02111, USA
bDepartment of Plant Foods Science and Technology, Instituto del
Frío-CSIC, E-28040 Marid, Spain
cUnit of Vitamins, Section of Nutrition, Clínica Puerta de Hierro,
28035 Madrid, Spain

Available online 15 August 2005.

Abstract
Consumption of fruits and vegetables is associated with a reduced risk
of death from all causes including heart disease and stroke. In this
work, the bioavailability of vitamin C from a Mediterranean vegetable
soup (gazpacho) constituted mainly of tomato, pepper and cucumber, and
its influence on plasma vitamin C, 8-epi-prostaglandin F2a
(8-epi-PGF2a), prostaglandin E2 (PGE2), monocyte chemotactic protein-1
(MCP-1), and the cytokines/tumor necrosis factor-a (TNF-a),
interleukin-1ß (IL-1ß), and IL-6 concentrations in a healthy human
population were assessed. Six men and six women consumed 500 ml of
commercial gazpacho per day for 14 days, corresponding to an intake of
78 mg of ascorbic acid per day. There were no differences (P=.22) in
baseline plasma vitamin C concentrations between the men and women. The
maximum increase (P<.05) in plasma vitamin C occurred 4 h postdose in
both men and women. Vitamin C concentrations were significantly higher
(P<.03) on Days 7 and 14 of the intervention. Baseline concentrations
of uric acid and 8-epi-PGF2a were significantly higher (P=.032) in men
than in women. Baseline concentrations of 8-epi-PGF2a decreased
significantly (P=.05) by Day 14 of the intervention. A significant
inverse correlation was observed between vitamin C and 8-epi-PGF2a
(r=-.415, P=.049). Baseline concentrations of PGF2 and MCP-1 were
significantly higher (P=.025) in men than in women but decreased
significantly (P=.05) by Day 14 of the intervention. No effect on
TNF-a, IL-1ß and IL-6 was observed at Day 14 of the intervention.
Drinking gazpacho (500 ml/day) significantly increases plasma
concentrations of vitamin C and significantly decreases 8-epi-PGF2a,
PGE2 and MCP-1 concentrations in healthy humans.

Keywords: Vegetable soup; Vitamin C; Bioavailability; F2-Isoprostanes;
Uric acid; Cytokines; Inflammatory markers

Supported in part by the Coordinated Grant CAM 07G/0040/2000-CAM
07G/0041/2000 (Comunidad Autónoma de Madrid), the Grant
AGL2002-04059-C02-02 (Ministry of Science and Technology, Madrid,
Spain) (MPC); a Fulbright/Ministry of Education, Culture and Sports
Award for Postdoctoral Research in the United States of America,
Visiting Scholar Program, Commission for Cultural, Educational and
Scientific Exchange between the United States of America and Spain, and
a Ramón y Cajal Research Contract (Ministry of Science and Technology,
Madrid, Spain) (CS-M). An earlier version of this article was presented
at Experimental Biology 2004, Washington DC, USA, April 2004.
Corresponding author. Department of Plant Foods Science and Technology,
Instituto del Frío, Consejo Superior de Investigaciones Científicas
(CSIC), C/José Antonio Novais 10, Ciudad Universitaria, E-28040
Madrid, Spain. Tel.: +34 91 549 23 00, +34 91 544 56 07; fax: +34 91
549 36 27.

The Journal of Nutritional Biochemistry
Volume 17, Issue 3 , March 2006, Pages 183-189

Who loves ya.
Tom

Jesus Was A Vegetarian!
http://jesuswasavegetarian.7h.com

Man Is A Herbivore!
http://pages.ivillage.com/ironjustice/manisaherbivore

DEAD PEOPLE WALKING
http://pages.ivillage.com/ironjustice/deadpeoplewalking

Rob Duncan · medicine forum beginner Joined: 31 Aug 2005 Posts: 16

Cold soup is just gross, IMHO.

Rob

<pellmellwillynilly@hotmail.com> wrote in message
news:1141150993.950330.192400@j33g2000cwa.googlegroups.com...

Evelyn Ruut · medicine forum beginner Joined: 28 Apr 2005 Posts: 44

"Rob Duncan" <robtakethisoutduncan@gobigwest.com> wrote in message
news:wSiNf.5$ak3.140426@news.sisna.com...

Michael · medicine forum beginner Joined: 04 May 2005 Posts: 47

Don't knock it, Rob...

I was weaned straight from mom's tit to mom's gazpacho, and it's so good
I've never looked back. :-)

"Rob Duncan" <robtakethisoutduncan@gobigwest.com> wrote in message
news:wSiNf.5$ak3.140426@news.sisna.com...

Rob Duncan · medicine forum beginner Joined: 31 Aug 2005 Posts: 16

I cant think of a better recomendation. Maybe its time I expand my
horizons...

Rob

"Michael" <muirhead@haidagwaii.net> wrote in message
news:EaOdnVSfmP_qZJjZnZ2dnUVZ_sSdnZ2d@qcislands.net...

Michael · medicine forum beginner Joined: 04 May 2005 Posts: 47

Gaspacho
http://soup.allrecipes.com/az/88986.asp
and some tortilla chips with salsa verde and guacamole to dip 'em in
http://www.cooks.com/rec/doc/0,161,155163-242201,00.html
http://vegetarian.allrecipes.com/az/MexicanGuacamole.asp

as appies for an entrée of Mole chicken
http://chicken.allrecipes.com/az/SprChicknMl.asp
and nachos done up special-like
http://maindish.allrecipes.com/az/NchLsgn.asp

Don't forget the margaritas before, the lime Coronas with, and for dessert,
some sweet sopaipillas rellenos
http://dessert.allrecipes.com/az/90281.asp (use really ripe mango and a bit
of lime juice instead of pineapple, and add a tiny bit of cocoa and allspice
to the sugar)
with coffee & Kaluha. :-)

Besides, mom's tits are dry anyhow. :-P

Rob Duncan wrote:

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