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Gouoldt@aol.net
medicine forum beginner
Joined: 17 Sep 2005
Posts: 2
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 Posted: Sat Sep 17, 2005 12:28 pm Post subject:
Re: Find VIAGRA, CIALIS, LEVITRA at the best price?
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| Quote: | Which is it the site that has quality and a good price?
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Hi,
http://www.generic-medicines.net
G. |
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Jeff
medicine forum Guru
Joined: 25 Mar 2005
Posts: 1313
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| Posted: Sun Sep 18, 2005 5:59 pm Post subject:
Re: Long-Term Use of Azithromycin as anti-inflammatory?
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"MS" <ms@nospam.com> wrote in message
news:1126980731.143440@news-1.nethere.net...
| Quote: | In the following Medscape article, long-term use of the macrolide
antibiotic
azithromycin ("Zithromax") has been shown to have benefit in cystic
fibrosis, in children and adults, with little negative side effects. Not
used for its antibacterial properties, but for its anti-inflammatory
properties, which it has been found to have.
Has this also been prescribed in such a manner for chronic sinusitis? I
wonder if it could be helpful?
|
You are comparing apples and oranges. Chronic sinusitis is different in
important ways from the chronic infections in cystic fibrosis.
You can go to scholar.google.com or www.pubmed.gov and do your own search
using keywords like azithromycin and chronic sinusitis.
| Quote: | Finding a safe anti-inflammatory medication is a problem--as long-term
usage
of oral corticosteroids has harmful effects, and there are also negative
effects from long-term NSAID usage.
|
And there may be long-term problems from using azithromycin, as well.
Considering the long-term problems of having cystic fibrosis vs. the risks
from using azithromycin chronically, the benefits of azythromycin may
outweigh the risks, while in chronic sinusitis, they may not.
It sounds like you need to find out what is causing your chronic sinusitis
rather than treat the inflammation.
Jeff |
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MS
medicine forum addict
Joined: 28 Jun 2005
Posts: 58
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| Posted: Mon Sep 19, 2005 6:02 pm Post subject:
Re: Long-Term Use of Azithromycin as anti-inflammatory?
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f
"Jeff" <kidsdoc2000@hotmail.com> wrote in message
news:lGjXe.251$vw6.5@newsread1.news.atl.earthlink.net...
| Quote: |
You are comparing apples and oranges. Chronic sinusitis is different in
important ways from the chronic infections in cystic fibrosis.
|
Yes, they are two different diseases. But there are some connections. I have
read they have found a similar gene connected to both diseases. Both involve
chronic inflammation involving respiratory airways. But yes, not the same
disease. I didn't imply they were. Just that on reading an article how a
particular medication is used to control chronic inflammation in one
disease, one wonders whether it could also be helpful for other chronic
inflammatory diseases. Perhaps arthritis as well. I don't know, just
wondering.
| Quote: |
You can go to scholar.google.com or www.pubmed.gov and do your own search
using keywords like azithromycin and chronic sinusitis.
|
Well, I obviously did do some searching, which brought me to the article I
posted from Medscape. (I forget which search terms I used, which brought me
to that article.) Yes, I could do a search for the terms azithromycin and .
I would probably come across results listing azithromycin as one of the
antibiotics used in treating sinusitis. Not likely to find one on use as a
long-term anti-inflammatory in chronic sinusitis, but I guess it's possible.
Again, I was just speculating on a possible use, not positing that it is
already used that way.
| Quote: |
Finding a safe anti-inflammatory medication is a problem--as long-term
usage
of oral corticosteroids has harmful effects, and there are also negative
effects from long-term NSAID usage.
And there may be long-term problems from using azithromycin, as well.
Considering the long-term problems of having cystic fibrosis vs. the risks
from using azithromycin chronically, the benefits of azythromycin may
outweigh the risks, while in chronic sinusitis, they may not.
|
Of course. All medications have side effects, and the doctor needs to weigh
the benefits vs. risks in prescribing them. As I wrote though,
anti-inflammatories in particular have serious problems with side effects,
even the OTC ones. Would you consider long-term use of azythromycin to be
more risky than long-term use of prednisone, for example? Or even long-term
high dosages of ibuprofen? Yes, of course, risks and benefits always have to
be weighed, when considering medications.
| Quote: | It sounds like you need to find out what is causing your chronic sinusitis
rather than treat the inflammation.
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I've been doing that all my life. Sure I would prefer to cure it (by finding
out the "cause", and changing that), than deal with symptoms. But
unfortunately, there is no easy answer, as of yet certainly no cure. (Do you
have chronic sinusitis, or do you treat it frequently as an ENT or
allergist?) It is a far more serious and widespread disease than many people
realize. |
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Woody Long
medicine forum beginner
Joined: 26 Feb 2005
Posts: 6
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| Posted: Sat Sep 24, 2005 5:32 pm Post subject:
Re: Long-Term Use of Azithromycin as anti-inflammatory?
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| Quote: |
Of course. All medications have side effects, and the doctor needs to weigh
the benefits vs. risks in prescribing them. As I wrote though,
anti-inflammatories in particular have serious problems with side effects,
even the OTC ones. Would you consider long-term use of azythromycin to be
more risky than long-term use of prednisone, for example? Or even long-term
high dosages of ibuprofen?
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For long term use I would rate azithromycin as roughly 10x more harmful
than prednisone (depending on the dose of each), with prednisone being
again 10x more harmful than the maximum recommended dose of ibuprofen.
Unlike the others, ibuprofen will not worsen your underlying disease
(although it may cause other problems)
Worst of all would be prednisone and azithromycin simultaneously -
probably > 10x more dangerous than either one alone.
Woody |
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Woody Long
medicine forum beginner
Joined: 26 Feb 2005
Posts: 6
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| Posted: Sat Sep 24, 2005 5:32 pm Post subject:
Re: Long-Term Use of Azithromycin as anti-inflammatory?
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| Quote: |
Of course. All medications have side effects, and the doctor needs to weigh
the benefits vs. risks in prescribing them. As I wrote though,
anti-inflammatories in particular have serious problems with side effects,
even the OTC ones. Would you consider long-term use of azythromycin to be
more risky than long-term use of prednisone, for example? Or even long-term
high dosages of ibuprofen?
|
For long term use I would rate azithromycin as roughly 10x more harmful
than prednisone (depending on the dose of each), with prednisone being
again 10x more harmful than the maximum recommended dose of ibuprofen.
Unlike the others, ibuprofen will not worsen your underlying disease
(although it may cause other problems)
Worst of all would be prednisone and azithromycin simultaneously -
probably > 10x more dangerous than either one alone.
Woody |
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Sbharris[atsign]ix.netcom
medicine forum Guru
Joined: 28 Apr 2005
Posts: 1218
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| Posted: Sat Sep 24, 2005 11:06 pm Post subject:
Re: Long-Term Use of Azithromycin as anti-inflammatory?
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Woody Long wrote:
| Quote: | For long term use I would rate azithromycin as roughly 10x more harmful
than prednisone (depending on the dose of each),
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And why is that? |
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MS
medicine forum addict
Joined: 28 Jun 2005
Posts: 58
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| Posted: Mon Sep 26, 2005 4:50 am Post subject:
Re: Long-Term Use of Azithromycin as anti-inflammatory?
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"Sbharris[atsign]ix.netcom.com" <sbharris@ix.netcom.com> wrote in message
news:1127610412.280016.58620@g47g2000cwa.googlegroups.com...
| Quote: |
Woody Long wrote:
For long term use I would rate azithromycin as roughly 10x more harmful
than prednisone (depending on the dose of each),
And why is that?
|
He (Woody Long) does not reply, as to why he makes such a statement. I
suspect he just made up those figures with no basis for them, with his
statement about each being ten times more harmful than the next. (Quite
convenient in our decimal system, no, that everything is "ten times more
harmful"?)
Long term oral steroid usage, and long term high dosage NSAIDS usage, will
have definite serious side effects to anyone so using them. It is possible
that some people might have severe reactions to azithromycin, but I don't
think most people do,
Well, Woody, if there is a basis for your statements, please elaborate.
Thank you. |
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Bob Travis
medicine forum beginner
Joined: 10 Sep 2005
Posts: 40
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| Posted: Mon Sep 26, 2005 5:39 am Post subject:
Re: diseases of rich deprive poor of drugs
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But look at all the pills the pharmacy companies give away every year in
patient assistance programs. In my opinion the rich have it made, the poor
have it made too, only the working slobs get screwed (unless they're among
the few lucky enough to have a job with health insurance, but then they
still get screwed along with the rich, paying enough in taxes to fund all
the free health care for the poor people). It's only the middle class that
gets screwed because they can't afford to lobby for their rights as the rich
can, and the rich the need to feel justified in having all their wealth so
they may sometimes help out the poor to show how virtuous they are. In the
end who cares because you're either rich in spirit or psychological strength
or you're not, and if you are then you are rich in every sense, and if
you're not you cannot even buy happiness because you are still trying to
decide what constitutes happiness.
"Sbharris[atsign]ix.netcom.com" <sbharris@ix.netcom.com> wrote in message
news:1126657751.234791.14670@g44g2000cwa.googlegroups.com...
| Quote: |
Dr. Wayne Simon wrote:
the analogy of magazine prices in reference to advertizing, or newspaper
prices, with prescription medication prices, is not really a workable
economic comparison.
COMMENT:
And just why not? I rather liked it. The marginal cost of producing an
additional number of pills, once you've got the drug and the license to
sell it, is pretty darned small in comparison to all the rest.
SBH
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Happy Dog
medicine forum Guru
Joined: 05 May 2005
Posts: 336
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| Posted: Mon Sep 26, 2005 6:18 am Post subject:
Re: diseases of rich deprive poor of drugs
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"Bob Travis" <e_quip@hotmail.com> wrote in message news:
| Quote: | But look at all the pills the pharmacy companies give away every year in
patient assistance programs. In my opinion the rich have it made, the poor
have it made too, only the working slobs get screwed (unless they're among
the few lucky enough to have a job with health insurance, but then they
still get screwed along with the rich, paying enough in taxes to fund all
the free health care for the poor people).
|
Correct.
| Quote: | It's only the middle class that gets screwed because they can't afford to
lobby for their rights as the rich can, and the rich the need to feel
justified in having all their wealth so they may sometimes help out the
poor to show how virtuous they are.
|
Well, they are paying for it no matter what their motivation.
In the
| Quote: | end who cares because you're either rich in spirit or psychological
strength or you're not, and if you are then you are rich in every sense,
and if you're not you cannot even buy happiness because you are still
trying to decide what constitutes happiness.
|
Assuming that you've discovered it, retaining an additional 50% of your
income and disposing of it as you wish is unlikely to make you any less
happy.
moo |
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Bob Travis
medicine forum beginner
Joined: 10 Sep 2005
Posts: 40
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| Posted: Tue Sep 27, 2005 5:49 pm Post subject:
Re: diseases of rich deprive poor of drugs
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"Happy Dog" <happydog@sympatico.ca> wrote in message
news:w7OZe.545$l03.110452@news20.bellglobal.com...
| Quote: | "Bob Travis" <e_quip@hotmail.com> wrote in message news:
end who cares because you're either rich in spirit or psychological
strength or you're not, and if you are then you are rich in every sense,
and if you're not you cannot even buy happiness because you are still
trying to decide what constitutes happiness.
Assuming that you've discovered it, retaining an additional 50% of your
income and disposing of it as you wish is unlikely to make you any less
happy.
|
I'll agree that sounds believeable, but being a poor slob I have no
experential evidence to go on, so I'll take your word for it.  |
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Woody Long
medicine forum beginner
Joined: 26 Feb 2005
Posts: 6
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| Posted: Thu Sep 29, 2005 7:23 pm Post subject:
Re: Long-Term Use of Azithromycin as anti-inflammatory?
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MS wrote:
| Quote: | "Sbharris[atsign]ix.netcom.com" <sbharris@ix.netcom.com> wrote in message
news:1127610412.280016.58620@g47g2000cwa.googlegroups.com...
Woody Long wrote:
For long term use I would rate azithromycin as roughly 10x more harmful
than prednisone (depending on the dose of each),
And why is that?
He (Woody Long) does not reply, as to why he makes such a statement. I
suspect he just made up those figures with no basis for them, with his
statement about each being ten times more harmful than the next. (Quite
convenient in our decimal system, no, that everything is "ten times more
harmful"?)
|
Notice I qualified my statement with "roughly" and "depending on the
dose"
| Quote: |
Long term oral steroid usage, and long term high dosage NSAIDS usage, will
have definite serious side effects to anyone so using them. It is possible
that some people might have severe reactions to azithromycin, but I don't
think most people do,
Well, Woody, if there is a basis for your statements, please elaborate.
|
After only 10 days "C. albicans-colonized mice treated with each
macrolide had highly significant increase in colony counts of C.
albicans in their stools compared to C. albicans-colonized mice treated
with saline only"
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12058726&query_hl=1
The increase in colony count will vary by individual but lets say it
doubles after 10 days. Since organisms tend to grow exponentially,
after 1 year (say 360 days) of continuous uninterrupted use, the fungal
colony count could be as much as 2^36 higher or 68719476736.
This will make your underlying disease worse.
http://www.medicineatmichigan.org/magazine/2004/fall/huron/huron01.asp
And while you may not notice a modest 2 fold fungal colony count
increase you are very likely to notice a 68719476736-fold increase.
Therefore, I would not touch the stuff if I were you, but I realize you
will probably ignore this advice regardless.
If you do decide to take it long term, best of luck to you, and please
report back as to how sick you are or are not after 1 year of use.
Woody
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MS
medicine forum addict
Joined: 28 Jun 2005
Posts: 58
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| Posted: Sun Oct 02, 2005 3:58 pm Post subject:
Re: Long-Term Use of Azithromycin as anti-inflammatory?
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"Woody Long" <woodylong30@hotmail.com> wrote in message
news:1128029024.458258.34960@o13g2000cwo.googlegroups.com...
| Quote: | And while you may not notice a modest 2 fold fungal colony count
increase you are very likely to notice a 68719476736-fold increase.
|
Are you saying that use of azithromycin increases fungi in the body? Would
you say that is true for all antibiotics in general? All macrolides?
| Quote: | Therefore, I would not touch the stuff if I were you, but I realize you
will probably ignore this advice regardless.
If you do decide to take it long term, best of luck to you, and please
report back as to how sick you are or are not after 1 year of use.
|
I wouldn't be in the position to make such a decision. This medication is
not available OTC, I cannot just decide to start taking it long-term. After
reading about it being prescribed long-term as an anti-inflammatory for
cystic fibrosis, I was only speculating whether it might be useful as an
anti-inflammatory for other conditions as well.
When you write "I would not touch the stuff", are you saying that you never
take an antibiotic, or that you would never take azithromycin, or any
macrolides, not even short-term? |
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Woody Long
medicine forum beginner
Joined: 26 Feb 2005
Posts: 6
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| Posted: Tue Oct 04, 2005 8:05 pm Post subject:
Re: Long-Term Use of Azithromycin as anti-inflammatory?
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| Quote: | Are you saying that use of azithromycin increases fungi in the body? Would
you say that is true for all antibiotics in general? All macrolides?
|
Yes it seems all antibiotics have the potential to increase fungi in
the body. However, it appears that some have a greater potential than
others (e.g macrolides appear to be worse than penicillin)
| Quote: |
Therefore, I would not touch the stuff if I were you, but I realize you
will probably ignore this advice regardless.
If you do decide to take it long term, best of luck to you, and please
report back as to how sick you are or are not after 1 year of use.
I wouldn't be in the position to make such a decision. This medication is
not available OTC, I cannot just decide to start taking it long-term. After
reading about it being prescribed long-term as an anti-inflammatory for
cystic fibrosis, I was only speculating whether it might be useful as an
anti-inflammatory for other conditions as well.
When you write "I would not touch the stuff", are you saying that you never
take an antibiotic, or that you would never take azithromycin, or any
macrolides, not even short-term?
|
I would take an antibiotic (including a macrolide) short term, if I
needed it, like for a gunshot wound in the leg that got infected with
flesh eating bacteria, syphilis, anthrax, or something like that. I
would take the best antibiotic for whatever type of infection I had.
Usually only a short course of a few weeks or less is needed even for
very severe infections, when such infections are actually caused by
bacteria.
What I would not do is take an antibiotic for something not imminently
life threatening, or use it as an anti-inflammatory.
The fact that antibiotics act as anti-inflammatory is interesting
because it means that just because you take it and feel better, you
CANNOT assume that bacteria were contributing to your symptoms.
Woody |
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Woody Long
medicine forum beginner
Joined: 26 Feb 2005
Posts: 6
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| Posted: Tue Oct 04, 2005 8:05 pm Post subject:
Re: Long-Term Use of Azithromycin as anti-inflammatory?
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| Quote: | Are you saying that use of azithromycin increases fungi in the body? Would
you say that is true for all antibiotics in general? All macrolides?
|
Yes it seems all antibiotics have the potential to increase fungi in
the body. However, it appears that some have a greater potential than
others (e.g macrolides appear to be worse than penicillin)
| Quote: |
Therefore, I would not touch the stuff if I were you, but I realize you
will probably ignore this advice regardless.
If you do decide to take it long term, best of luck to you, and please
report back as to how sick you are or are not after 1 year of use.
I wouldn't be in the position to make such a decision. This medication is
not available OTC, I cannot just decide to start taking it long-term. After
reading about it being prescribed long-term as an anti-inflammatory for
cystic fibrosis, I was only speculating whether it might be useful as an
anti-inflammatory for other conditions as well.
When you write "I would not touch the stuff", are you saying that you never
take an antibiotic, or that you would never take azithromycin, or any
macrolides, not even short-term?
|
I would take an antibiotic (including a macrolide) short term, if I
needed it, like for a gunshot wound in the leg that got infected with
flesh eating bacteria, syphilis, anthrax, or something like that. I
would take the best antibiotic for whatever type of infection I had.
Usually only a short course of a few weeks or less is needed even for
very severe infections, when such infections are actually caused by
bacteria.
What I would not do is take an antibiotic for something not imminently
life threatening, or use it as an anti-inflammatory.
The fact that antibiotics act as anti-inflammatory is interesting
because it means that just because you take it and feel better, you
CANNOT assume that bacteria were contributing to your symptoms.
Woody |
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Ernie Sty
medicine forum beginner
Joined: 27 Sep 2005
Posts: 4
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| Posted: Thu Oct 06, 2005 3:57 pm Post subject:
Re: SSRI-Induced SEXUAL DYSFUNCTION, assorted remedies for....
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"Dave Bird" <dave.xemu.deleteThe@nospam.demon.co.uk> wrote in message
news:Wg6XNfA$wnNBFwnL@xemu.demon.co.uk...
| Quote: | In article<89c8d6f6.0408311232.4d40816f@posting.google.com>, john russel
john_r78@hotmail.com> writes:
Hi,
About a year ago a new doctor switched me from Paxil to Prozac,
because the Paxil seemed to have burnt out (after 2 years). After 3
days on Prozac I had an unusual orgasm, where there was a long (4
seconds?) delay after the orgasm started (no pulsing) and before
ejaculation, and then the semen just ran out, it didn't "shoot" as
usual. The next orgasm, 2 days later, was more normal and did not have
the delay, but the semen just ran out again, and the feeling was not
nearly as intense as normal. When the same thing happened again (a
couple days later) I quit taking the prozac. The change in orgasm
didn't go away, and the feeling is still not very intense - it's been
over a year now.
Is there anything I can do to correct this problem and be back to
normal? I cross-posted this to the prostate group, as someone there
may have an answer. There was never any pain during orgasm. I think it
would be quite a coincedence if I actually have a problem with my
prostate.
SSRIs often cause reduced, delayed, or no- orgasm. The effect is
less obvious with paxil than prozac, because paxil clears from the body
in about 2.5 days but prozac in about 21 days.
|
Three weeks? I thought it was more like four to six? |
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