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ironjustice@aol.com
medicine forum Guru
Joined: 28 Apr 2005
Posts: 1522
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 Posted: Sun May 28, 2006 8:29 pm Post subject:
Fanconi anemia / ANOTHER .. prize ?
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http://bentham.org/cmc/contabs/cmc12-23.htm#6
<<snip>>
findings concerning the discovery of iron-stimulated free radical
cascades in Fanconi anemia
<<snip>>
Superoxide and Nitric Oxide in Pathological Conditions Associated with
Iron Overload. The Effects of Antioxidants and Chelators
I.B. Afanas'ev
Free radicals are a one of damaging factors in diseases associated with
iron overload. This review considers two principal questions: the
mechanisms of free radical-mediated damage in cells and tissue and
findings concerning the discovery of iron-stimulated free radical
cascades in thalassemia and Fanconi anemia. There are two major
precursors of all reactive oxygen and nitrogen species formed in living
organism - superoxide (O2.-) and nitric oxide (NO). However, it has
been shown that in addition to well-known mechanisms of the formation
of reactive hydroxyl radicals and peroxynitrite from superoxide and NO,
there are signal pathways by which these "physiological" radicals
directly induce apoptosis, proton leak in mitochondria and an increase
in oxygen consumption leading to cell death. In present review the
mechanisms of free radical damage are considered with the particular
emphasis of iron-induced free radical formation in thalassemia and
Fanconi anemia. Furthermore free radical reactions leading to lipid
peroxidation, LDL oxidation, the stimulation of apoptosis and other
damaging processes are discussed. An importance of the chelating and
antioxidant treatments of thalassemic and Fanconi anemia patients is
also considered within the context of free radical damage and its
prevention.
http://www.cyto.purdue.edu/hmarchiv/1996/1661.htm
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://jesuswasavegetarian.7h.com
Man Is A Herbivore!
http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk |
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babawali@world.com
medicine forum addict
Joined: 29 Apr 2006
Posts: 81
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| Posted: Sun May 28, 2006 8:29 pm Post subject:
Re: Fanconi anemia / ANOTHER .. prize ?
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Similar language, no prize no cigar, "iron overload" says it all, don't
book a trip to oslo just yet. As the language of the abstract directly
implies, the overload, not presence of normal levels, is one among other
paths to the disorders. All you have "discovered" is that researchers
often have common thinking and often are reacting to the research of each
other, you have made no contribution in the least. Crude amateur agenda
driven unrelated irrelevant musings aren't prize worthy. |
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ironjustice@aol.com
medicine forum Guru
Joined: 28 Apr 2005
Posts: 1522
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Manky Badger
medicine forum Guru Wannabe
Joined: 01 May 2005
Posts: 158
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| Posted: Mon May 29, 2006 7:47 am Post subject:
Re: Fanconi anemia / ANOTHER .. prize ?
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<ironjustice@aol.com> wrote in message
news:1148861307.016903.125980@u72g2000cwu.googlegroups.com...
| Quote: | http://bentham.org/cmc/contabs/cmc12-23.htm#6
snip
particular emphasis of iron-induced free radical formation
snip
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So that is the ONLY and SOLE cause of disease in Fanconi's anaemia ?
*** Posted via a free Usenet account from http://www.teranews.com *** |
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babawali@world.com
medicine forum addict
Joined: 29 Apr 2006
Posts: 81
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| Posted: Mon May 29, 2006 11:37 am Post subject:
Re: Fanconi anemia / ANOTHER .. prize ?
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Here is the core part, iron plays a role in some of the cascades,
prooxidants are the cause of all types, read and weep:
"it has been shown that in addition to well-known mechanisms of the
formation of reactive hydroxyl radicals and peroxynitrite from
superoxide and NO, there are signal pathways by which these
"physiological" radicals directly induce apoptosis, proton leak in
mitochondria and an increase in oxygen consumption leading to cell
death. In present review the mechanisms of free radical damage are
considered with the particular emphasis of iron-induced free radical
formation in thalassemia and Fanconi anemia." |
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ironjustice@aol.com
medicine forum Guru
Joined: 28 Apr 2005
Posts: 1522
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babawali@world.com
medicine forum addict
Joined: 29 Apr 2006
Posts: 81
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| Posted: Mon May 29, 2006 2:28 pm Post subject:
Re: Fanconi anemia / ANOTHER .. prize ?
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Narrow snipping doesn't the truth change nor crude amateur agenda driven
thinking support, not close, no cigar, no prize period. his was said to
be in cases of iron overload in some examples of the apperance of the
disorder, silk purses of pig's ears aren't made, nuff said. |
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babawali@world.com
medicine forum addict
Joined: 29 Apr 2006
Posts: 81
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| Posted: Mon May 29, 2006 7:32 pm Post subject:
Re: Fanconi anemia / ANOTHER .. prize ?
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No cigar, no prize, no trip to nordic regions; same old same old amateur
agenda driven glock, now if we invent a glock prize, hmmm... |
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ironjustice@aol.com
medicine forum Guru
Joined: 28 Apr 2005
Posts: 1522
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babawali@world.com
medicine forum addict
Joined: 29 Apr 2006
Posts: 81
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| Posted: Mon May 29, 2006 10:36 pm Post subject:
Re: Fanconi anemia / ANOTHER .. prize ?
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Not only did you cheery pick that article but you cherry picked a few
words in such a way as to spin the meaning you wanted from it while
ignoring the other language that defeats your agenda driven goal. This is
one for the glock prize for the cherry picking division and for dishonest
use of research results. Repeating the cherry pick words doesn't save
them, it only highlights the lengths to which some will go no matter how
dishonest, or is it only the normal product of the crude amateur watching
the vision of glory going down the drain. |
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ironjustice@aol.com
medicine forum Guru
Joined: 28 Apr 2005
Posts: 1522
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| Posted: Mon May 29, 2006 11:22 pm Post subject:
Re: Fanconi anemia / ANOTHER .. prize ?
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Heh .. heh ..
Soooooo .. seems you are TARGETING my .. specific .. posts ..
With your .. drivel ..
The article says .. they are placing SPECIAL emphasis on free radical
... IRON .. induced .. damage ..
You seem to .. think .. this is .. unimportant .. ON / in these medical
newsgroups ..
Do .. ya .. ?
Ya .. fkg .. pussy ..
Heh .. heh ..
http://bentham.org/cmc/contabs/cmc12-23.htm#6
<<snip>>
particular emphasis of iron-induced free radical formation
<<snip>>
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://jesuswasavegetarian.7h.com
Man Is A Herbivore!
http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk |
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ironjustice@aol.com
medicine forum Guru
Joined: 28 Apr 2005
Posts: 1522
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| Posted: Tue May 30, 2006 1:09 am Post subject:
Re: Fanconi anemia / ANOTHER .. prize ?
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| Quote: | it only highlights the lengths to which some will go no matter how
dishonest, |
Doesn't it .. mr .. religion ..
Heh .. heh ..
Falsify any medical studies .. lately ..
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://jesuswasavegetarian.7h.com
Man Is A Herbivore!
http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk |
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babawali@world.com
medicine forum addict
Joined: 29 Apr 2006
Posts: 81
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| Posted: Tue May 30, 2006 2:48 pm Post subject:
Re: Fanconi anemia / ANOTHER .. prize ?
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Go in peace my friend. Bty, am I the first to mention that you are your
own worst enemy? My only reason for replying to your posts is to make
sure no one thinks the iron causes all disease notion has any validity. I
could probably not bother as your response to correction, flaws in logic,
failure to understand what is posted, etc. tells the story more forcefully
then the mere simple truth of my posts do. May God bless and protect you. |
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