Dizziness, dysesthesia, truncal ataxia / vitamin E

ironjustice@aol.com · medicine forum Guru Joined: 28 Apr 2005 Posts: 1522

No To Shinkei. 2005 Feb;57(2):145-8. Related Articles, Links

[Treatment of neurological complication due to postgastrectomy vitamin
E deficiency]

[Article in Japanese]

Ueda N, Suzuki Y, Takahashi T, Rino Y, Takanashi Y.

Department of Neurology, Yokohama City University School of Medicine.

Although postgastrectomy vitamin E deficiency rarely occurs, it can
cause neuromuscular disorder such as neuropathy, myopathy and
cerebellar ataxia. We encounter a lot of cases whose serum vitamin E
level were decreased after gastrectomy. We evaluated the oral vitamin E
intake as a therapy to these cases. The subjects of this study were 11
gastrectomized patients (8 patients had total gastrectomy, 2 subtotal
gastrtectomy, 1 partial gastrectomy) with decreased vitamin E. 10
patients had neurological complications such as dizziness, dysesthesia,
truncal ataxia. Serum vitamin E increased to normal level in 10
patients and neurological disturbances were improved in 9 patients. The
minimum requirement of oral vitamin E intake was 150 mg a day for
normalization of serum vitamin E, on the other hand, it decreased with
150 mg intake in some patients. Their serum level increased with 300
mg. We suggest that it is important to check serum vitamin E in
gastrectomized patients and oral vitamin E should be supplied over 300
mg for the therapy with vitamin E deficiency.

PMID: 15856761 [PubMed - indexed for MEDLINE]

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