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What other renal cancer treatments should a man try? (X ray chest shots)
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madiba
medicine forum Guru Wannabe


Joined: 05 Jul 2005
Posts: 203

PostPosted: Tue Mar 28, 2006 11:29 am    Post subject: Re: What other renal cancer treatments should a man try? (X ray chest shots) Reply with quote

k <kopn@hotbox.ru> wrote:

Quote:
Hello
X ray chest shots of a man, born 1951, are on
http://kopn.narod.ru/chest
His left kidney with a 4 cm tumor was removed in december 2004. Lymph
nodes in his chest did not grow from the nephrectomy up to October,
2005. He received Roferon (interferon alfa 2) 3ME subcutaneously from
January to March, 2006 everyday in three courses of 10 days with a two
week rest. The Roferon made him weaker, loose 7 kg and cough more;
increased two biggest lymph nodes by 5 mm in his chest. What other
treatments should he try in Moscow, Russia? What is a prognosis for him?

Could try the tyrosine kinase inhibitors, VEGFR-mAb etc such as
sorafenib, imatinib, bevacizumab or temsirolimus. Nexavar (sorafenib) in
particular is being toted as improving survival after phase III trials.
These drugs offer a respite, not a cure of the disease so his prognosis
remains poor.

madiba
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k
medicine forum beginner


Joined: 15 Mar 2006
Posts: 19

PostPosted: Tue Mar 28, 2006 1:04 pm    Post subject: Re: What other renal cancer treatments should a man try? (X ray chest shots) Reply with quote

Thanks madiba for your reply.
How long will he live?
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madiba
medicine forum Guru Wannabe


Joined: 05 Jul 2005
Posts: 203

PostPosted: Tue Mar 28, 2006 5:34 pm    Post subject: Re: What other renal cancer treatments should a man try? (X ray chest shots) Reply with quote

k <kopn@hotbox.ru> wrote:

Quote:
Thanks madiba for your reply.
How long will he live?

8 months and 2 days..




Seriously,
I don't have a crystal ball, no predictions here.
You haven't even given a proper stage as in TNM etc

--
madiba
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k
medicine forum beginner


Joined: 15 Mar 2006
Posts: 19

PostPosted: Wed Mar 29, 2006 11:53 am    Post subject: Re: What other renal cancer treatments should a man try? (X ray chest shots) Reply with quote

Thanks madiba for replying.
His lymph nodes on http://chestshot.narod.ru are enlarged. This is the
only discovered abnormality in his body in the last year. His surgeons
said that lymph nodes near his kidneys were not enlarged, were normal
when they removed his left kidney. Is it T0N1M0 now?
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madiba
medicine forum Guru Wannabe


Joined: 05 Jul 2005
Posts: 203

PostPosted: Thu Mar 30, 2006 10:37 am    Post subject: Re: What other renal cancer treatments should a man try? (X ray chest shots) Reply with quote

k <kopn@hotbox.ru> wrote:

Quote:
Thanks madiba for replying.
His lymph nodes on http://chestshot.narod.ru are enlarged. This is the
only discovered abnormality in his body in the last year. His surgeons
said that lymph nodes near his kidneys were not enlarged, were normal
when they removed his left kidney. Is it T0N1M0 now?

I looked at the website, but its very slow and takes an hour or more to
load all of those x-rays, I dont have the time. Removing the old x-rays
should speed it up a bit but the site needs broadband.
What I did see was a close-up of the right costophrenic angle and that
looked like an intrapulmon. metastasis of about 4cm... in fact as I type
this the x-rays start coming and he seems to have multiple lung mets..
For a more accurate interpretation of this case a CT of chest and
abdomen is needed, with coronal reconstruction (makes interpreting the
films much quicker). Provisional stage T1 N2 M1
Prognosis of less than a year.

--
madiba
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k
medicine forum beginner


Joined: 15 Mar 2006
Posts: 19

PostPosted: Fri Mar 31, 2006 6:45 am    Post subject: Re: What other renal cancer treatments should a man try? (X ray chest shots) Reply with quote

Thanks maliba for your estimation.
His radiologist said that the mets are in lymph nodes in his chest, not
intrapulmon. metastasis. Is she wrong?
They made CT in november 2004 and found only the enlaged lymph nodes
outside his left kidney. His sergeon removed his left kidney in
december 2004.
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k
medicine forum beginner


Joined: 15 Mar 2006
Posts: 19

PostPosted: Fri Mar 31, 2006 6:48 am    Post subject: Re: What other renal cancer treatments should a man try? (X ray chest shots) Reply with quote

Dear maliba,
Did you mean http://chestshot.narod.ru/index_files/image003.jpg by the
right costophrenic angle?
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k
medicine forum beginner


Joined: 15 Mar 2006
Posts: 19

PostPosted: Fri Mar 31, 2006 8:26 am    Post subject: Re: What other renal cancer treatments should a man try? (X ray chest shots) Reply with quote

Dear maliba,
I copied the chest shots site to speedier http://ch.0catch.com and
http://www.ch.0catch.com
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madiba
medicine forum Guru Wannabe


Joined: 05 Jul 2005
Posts: 203

PostPosted: Mon Apr 03, 2006 8:03 pm    Post subject: Re: What other renal cancer treatments should a man try? (X ray chest shots) Reply with quote

k <kopn@hotbox.ru> wrote:

Quote:
Thanks maliba for your estimation.
His radiologist said that the mets are in lymph nodes in his chest, not
intrapulmon. metastasis. Is she wrong?
She's wrong. The mediastinal nodes are very large, but the patient also

has intrapulmonary mets.

Quote:
They made CT in november 2004 and found only the enlaged lymph nodes
outside his left kidney.
"outside his left kidney" is not a defined anatomical region.

Were the LNs around the kidney hilus, along the renal veins or within
the paraaortal LN group? Did the surgeon remove the nodes, were they
positive histologically? Did the tumor grown INTO the renal vein?
Whatever, the patient is now stage IV.


--
madiba
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madiba
medicine forum Guru Wannabe


Joined: 05 Jul 2005
Posts: 203

PostPosted: Mon Apr 03, 2006 8:03 pm    Post subject: Re: What other renal cancer treatments should a man try? (X ray chest shots) Reply with quote

k <kopn@hotbox.ru> wrote:

Quote:
Dear maliba,
I copied the chest shots site to speedier http://ch.0catch.com and
http://www.ch.0catch.com

Yes, much faster. Pity about the audio ads...

--
madiba
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k
medicine forum beginner


Joined: 15 Mar 2006
Posts: 19

PostPosted: Tue Apr 04, 2006 7:25 am    Post subject: Re: What other renal cancer treatments should a man try? (X ray chest shots) Reply with quote

Thanks maliba for your important reply.
I meant They made CT in november 2004 and found only the enlaged lymph
nodes in his chest, not near his left kidney. The LNs around the kidney
hilus, along the renal veins and within the paraaortal LN group were
normal. The surgeon did not remove the nodes, they were not positive
histologically. The tumor did not grow INTO the renal vein.
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k
medicine forum beginner


Joined: 15 Mar 2006
Posts: 19

PostPosted: Tue Apr 04, 2006 8:56 am    Post subject: Re: What other renal cancer treatments should a man try? (X ray chest shots) Reply with quote

Thanks madiba for your important reply.
I meant They made CT in november 2004 and found only the enlaged lymph
nodes in his chest, not near his left kidney. The LNs around the kidney

hilus, along the renal veins and within the paraaortal LN group were
normal. The surgeon did not remove the nodes, they were not positive
histologically. The tumor did not grow INTO the renal vein.
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k
medicine forum beginner


Joined: 15 Mar 2006
Posts: 19

PostPosted: Tue Apr 04, 2006 8:57 am    Post subject: Re: What other renal cancer treatments should a man try? (X ray chest shots) Reply with quote

Dear madiba,
Did you mean http://chestshot.narod.ru/index_files/image003.jpg by the
right costophrenic angle?
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k
medicine forum beginner


Joined: 15 Mar 2006
Posts: 19

PostPosted: Tue Apr 04, 2006 8:58 am    Post subject: Re: What other renal cancer treatments should a man try? (X ray chest shots) Reply with quote

Thanks madiba for your estimation.
His radiologist said that the mets are in lymph nodes in his chest, not

intrapulmon. metastasis. Is she wrong?
They made CT in november 2004 and found only the enlaged lymph nodes
outside his left kidney. His sergeon removed his left kidney in
december 2004.
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madiba
medicine forum Guru Wannabe


Joined: 05 Jul 2005
Posts: 203

PostPosted: Tue Apr 04, 2006 1:31 pm    Post subject: Re: What other renal cancer treatments should a man try? (X ray chest shots) Reply with quote

k <kopn@hotbox.ru> wrote:

Quote:
Thanks maliba for your important reply.
I meant They made CT in november 2004 and found only the enlaged lymph
nodes in his chest, not near his left kidney. The LNs around the kidney
hilus, along the renal veins and within the paraaortal LN group were
normal.
Normal radiologically. That makes things clearer.


Quote:
The surgeon did not remove the nodes, they were not positive
histologically.
We don't know that as they were not sent to the path lab. In fact it can

now be assumed that they would have been positive histologically had
they been removed..

Quote:
The tumor did not grow INTO the renal vein.
So he was T1 N2 V0 M0 originally.

After immunotherapy he is now stage IV.

--
madiba
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